Adaptive vs Conventional deep brain stimulation for Parkinson’s disease: a eight-hours study
Objective: To compare the clinical efficacy of unilateral conventional DBS (cDBS) vs adaptive DBS (aDBS) based on local field potentials (LFP) delivered for 8 hours…Reduced Striatal VMAT2 in REM Sleep Behavior Disorder: A Gateway to Preclinical Parkinson’s Disease
Objective: To determine the degree of striatal degeneration that occurs in subjects with REM Sleep Behavior Disorder (RBD) and assess whether this is an appropriate…Is probable REM sleep behavior disorder a risk factor of impulsive-compulsive behaviors in Parkinson’s disease? PPMI study
Objective: To assess the association of REM sleep behavior disorder (RBD) with the development of impulse compulsive behaviors (ICBs) in patients with early Parkinson’s disease (PD)…Alexithymia is associated with worse quality of life and caregiver burden in people with Parkinson’s disease
Objective: Aim of the present study was to determine the relationship of alexithymia on HR-QoL of the PwP and caregiver burden of the corresponding primary…Approach to the patients with the hallucinations, in the Parkinson’s disease in the low-income country and environment of restricted medications and stigmas
Objective: Expose the percentage of patients with hallucinations in studying group of Parkinson’s disease patients in Uzbekistan. Background: Uzbekistan has 35 million population, largest in…Sleep Disturbances in Young Onset Parkinson’s Disease
Objective: To assess the quality of sleep, incidence of RBD and excessive daytime sleepiness in Young Onset Parkinson’s disease patients. Background: Sleep disorders are one…Vitamin Deficiencies in Parkinson’s Disease: A Case for Routine Screening
Objective: Assess the prevalence and impact of vitamin deficiencies in Parkinson’s Disease (PD) and how nutritional intake correlates with serum levels. Background: Previous research has…Insomnia may have a mediating role in linking Parkinson’s disease severity to depression and anxiety
Objective: The aim of this study was to investigate the role of insomnia in relationship of disease severity with depression/anxiety in patients with Parkinson’s disease…Selective α-synuclein overexpression-induced pathology in noradrenergic neurons: a new mouse model for prodromal Parkinson’s disease?
Objective: To investigate the phenotype of noradrenergic (NA) neurons in an animal model with selective overexpression of α-synuclein (αSyn) in the locus coeruleus (LC) with…Spreading ɑ-synuclein pathology initiated from the sublaterodorsal tegmental nucleus models RBD followed by Parkinsonian phenotypes in mice
Objective: To recapitulate ɑ-synucleinopathy based RBD-like behaviors in mice which could further proceed to develop Parkinsonian behavioral and histopathological phenotypes. Background: Idiopathic REM sleep behavior…
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