Prevalence, Impact, and Suboptimal Treatment of Depression in the Fox Insight Cohort
Objective: Addressing unmet mental health needs in Parkinson’s disease (PD) requires delineating their scope and impact. This study evaluated (1) depressive symptom prevalence and treatment…Increased illusory responses in non-hallucinating, cognitively impaired Lewy body disease patients
Objective: To determine whether non-hallucinating Lewy body disease-spectrum patients report increased illusory responses. Background: Pareidolias are specific illusions of faces and objects perceived in formless…Using mindfulness to improve self-awareness in Parkinson’s disease patients – preliminary results of a randomized controlled trial
Objective: This clinical trial aims to investigate the effects and feasibility of a newly developed 8-week mindfulness intervention on self-awareness in Parkinson’s disease (PD) patients.…Blood-Brain Barrier Opening with Focused Ultrasound in Parkinson´s Disease with Cognitive Impairment: A Safety and Feasibility Study
Objective: To evaluate the safety and feasibility of MR guided focused ultrasound (MRgFUS) blood-brain barrier (BBB) opening in the cortex or the striatum in Parkinson´s…Enhancement of executive functions but not memory by multidomain cognitive group training in Parkinson patients with mild cognitive impairment: A multicenter randomized controlled trial
Objective: To determine cognitive training (CT) effects in Parkinson’s disease (PD) patients with mild cognitive impairment (PD-MCI) on cognitive and non-cognitive outcomes compared to an…Baseline results of a virtual longitudinal, observational study of Parkinson’s disease: The AT-HOME PD cohort
Objective: To describe the baseline characteristics of Parkinson’s disease (PD) clinical trial participants enrolled in a remote, long-term observational follow-up study. Background: Participation in clinical…Perspectives on care for late stage Parkinson’s disease
Objective: The aim of this study was to explore experiences of late stage Parkinson's disease (PD) patients' and their informal caregivers’ satisfaction with care and support,…Long-term effects of ADS-5102 (amantadine) extended release capsules on OFF symptoms in Parkinson’s disease patients with levodopa-induced dyskinesia: Analysis of EASE LID 2 trial
Objective: Evaluate the long-term effect of ADS-5102 on OFF time among Parkinson’s disease (PD) patients with levodopa-induced dyskinesia (LID). Background: ADS-5102, the only drug FDA-approved…Andrograholide protect microglial activation via inhibiting mitochondrial ROS generation and NLRP3 inflammasome activation in in-vitro and in-vivo model of Parkinson’s disease
Objective: Parkinson's disease (PD) is a distressing neurodegenerative disorder effecting nearly 2-3% of the total population greater than 65 years old . Several mechanisms have…The add-on effect of Lactobacillus plantarum PS128 in patients with Parkinson’s disease: A pilot study
Objective: We aimed to investigate the add-on effect of Lactobacillus plantarum PS128 (PS128) in patients with Parkinson’s disease (PD). Background: PS128 is a specific probiotic…
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