Deep Brain Stimulation impact on Social and Occupational Function in Parkinson’s Disease with Early Motor Complications
Objective: To investigate the effect of DBS compared with BMT on social, psychosocial and occupational functioning in PD patients ≤ 60 years of age with…Effect of Lactobacillus casei supplementation on clinical response, gut microbiota and faecal metabolites in patients with Parkinson’s disease: A randomized, double-blind, placebo-controlled trial
Objective: To evaluate the effect of Lactobacillus casei strain Shirota (LcS) supplementation on symptoms, gut microbiota and faecal metabolites in patients with Parkinson's disease (PD).…A Parkinson’s disease dog providing therapeutic intervention in Parkinson’s disease
Objective: To report a case of Parkinson’s disease gait impairment which responded favourably to intervention with an assistance dog. Background: Gait abnormalities including freezing of…Efficacy and security starting safinamide treatment with 100 mg/day in Parkinson’s disease
Objective: Evaluating the efficacy and security starting safinamide treatment with 100 mg/day in PD Background: Safinamide has a unique dopaminergic and non-dopaminergic mode of action…Effectiveness of Carbidopa/Levodopa Enteral Suspension (CLES) in Advanced Parkinson’s Disease (APD) Patients with Moderate to Severe Fatigue: Sub-group Analysis from PROviDE study
Objective: To examine the effect of CLES at 12 months of follow-up in APD patients with moderate to severe fatigue. Background: Fatigue, one of the…Quantitative study of T-type Ca2+ channels in the subthalamic nucleus neurons towards Parkinson’s disease
Objective: From the pathophysiological perspectives, Parkinson’s disease (PD) can be viewed as a prototypical disorder of “brain arrhythmias”. Therefore, the modulation of relevant ion channels…Noninvasive brain stimulation to treat hypokinetic dysarthria in PD: A sham stimulation-controlled trial
Objective: To treat hypokinetic dysarthria (HD) in PD patients using multiple sessions repetitive transcranial magnetic stimulation (rTMS) Background: Based on results from our rTMS exploratory…Efficacy and safety of levodopa-carbidopa intestinal gel (LCIG) for advanced Parkinson’s disease: a Turkish single-centre experience
Objective: This study is aimed to investigate the efficacy and adverse effect profile of LCIG among advanced PD patients from a Turkish movement disorder center.…Laryngeal movement disorders as a potential clinical biomarker in multiple system atrophy: Results from the LaPD study
Objective: To systematically assess frequency and nature of laryngeal dysfunction in multiples system atrophy (MSA) compared to Parkinson’s disease (PD) and to identify a potential…GCI-induced neurodegeneration and synucleinopathy in non-human primates
Objective: This study aimed at determining the potential to induce MSA pathology in non-human primates. Background: Aggregation of alpha-synuclein has been implicated in several neurodegenerative…
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