Long-term effects of air pollution on the risk of Parkinson’s disease
Objective: We aimed to investigate the association between air pollution, including fine particulate matter (particles 2.5 mm in diameter, or PM2.5), and the risk of…Premotor compensatory mechanisms in Parkinson’s disease with LRRK2-R1441H mutation
Objective: To investigate the time course of modifications in dopaminergic terminals during the premotor phase in LRRK2 genetically determined Parkinson’s disease (PD). Background: Increased dopamine…Video-to-Home Cognitive-Behavioral Therapy for Veterans with Depression and Parkinson’s Disease: A Randomized Controlled Trial
Objective: For the nearly 100,000 veterans with Parkinson’s disease (PD) receiving Veterans Affairs (VA) health care, depression is prevalent, yet often undiagnosed or undertreated. This…Mental Health Matters Too – Integration of physical and mental health in a multidisciplinary Parkinson’s Clinic
Objective: The overall aim of the project was to demonstrate that people with Parkinson’s disease benefit from good mental health care when mental health services…Effect of Combined Modality Treatment on Sustained Phonation in Parkinson’s Disease
Objective: To determine whether Lee Silverman Voice Treatment (LSVT-LOUD(R)) combined with Transcranial Magnetic Stimulation in individuals with Parkinson's disease (PD) improves phonation to a greater…Pridopidine for the treatment of Levodopa-induced Dyskinesia in patients with Parkinson’s disease
Objective: To assess the efficacy and safety of pridopidine in PD patients with Levodopa-induced dyskinesia (LID). Background: Pridopidine is a small molecule in clinical development…Phase I-II first-in-human clinical study of intraputamenal CDNF in Parkinson’s disease: Exploratory PET imaging endpoints of the 12-month treatment period
Objective: To test if intermittent intraputamenal monthly infusions of CDNF have an effect on striatal dopamine transporter (DAT) binding, as measured by PET, in subjects…CHIEF-PD: Cholinesterase Inhibitor to prEvent Falls in Parkinson’s Disease
Objective: Preventing falls in people with Parkinson’s disease has the potential to reduce hospital admissions and improve quality of life by diminishing the significant morbidity…Are effects of Rock Steady Boxing and PD SAFExTM on the motor symptoms of Parkinson’s disease maintained long-term? – A single-blinded randomized controlled trial
Objective: To determine if the benefits associated with RSB and PD SAFExTM on the motor symptoms of PD wash out over time. Background: Parkinson’s disease…Remote video-based research visits in a phase 3 clinical trial in Parkinson’s disease
Objective: To assess the feasibility, reliability, and value of remote visits in a phase 3 trial of individuals with Parkinson's disease (PD). Background: Remote video-based…
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