MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

MENU 
  • Home
  • Meetings Archive
    • 2024 International Congress
    • 2023 International Congress
    • 2022 International Congress
    • MDS Virtual Congress 2021
    • MDS Virtual Congress 2020
    • 2019 International Congress
    • 2018 International Congress
    • 2017 International Congress
    • 2016 International Congress
  • Keyword Index
  • Resources
  • Advanced Search

Long-term effects of air pollution on the risk of Parkinson’s disease

Y.S Hwang, S.Y Jo, Y.J Kim, K.W Park, S.H Lee, S.J Chung (Seoul, Republic of Korea)

Meeting: MDS Virtual Congress 2020

Abstract Number: 811

Keywords: Environmental toxins, Parkinsonism

Category: Parkinson's Disease: Pathophysiology

Objective: We aimed to investigate the association between air pollution, including fine particulate matter (particles 2.5 mm in diameter, or PM2.5), and the risk of Parkinson’s disease (PD).

Background: Several epidemiologic studies investigated the effect of exposure to air pollution on the risk of PD. However, the results were heterogenous between studies, and most of the studies were conducted in western countries. Therefore, long-term effect of air pollution on the risk of PD is needed to be further investigated.

Method: We identified 78,708 adults aged over 40 years, free of PD, and who lived in Seoul metropolitan city on 2002 to 2006 from the National Health Insurance Service -National Sample Cohort version 2.0 of Korea. Individuals were followed up until 31 December 2015 with 1,075,496 total person-years of follow-up. We assessed annual exposures to PM2.5 from Time-dependent Cox proportional hazards model. We analyzed annual mean PM2.5 concentration for 25 districts from Air quality information of Seoul Metropolitan Government. We applied time-dependent Cox proportional hazards models, adjusting for age, sex and health insurance type. The annual mean PM2.5 was used as the time-dependent variables.

Results: During the study period, we identified 332 newly diagnosed cases of PD. Each 10-μg/m3 increment in cumulative average PM2.5 exposure was not associated with PD (HR = 0.904; 95% CI = 0.599-1.370), after adjusting for age, sex, and health insurance type. Risk of PD was not significantly different between participants in the top quartile group (PM2.5: 31.0-55.0μg/m3) and participants in the lowest quartile group (PM2.5: 16.0-24.0μg/m3). Older age was associated with PD (HR = 1.108; 95% CI = 1.100-1.115). Study population in the Medicaid group had increased risk of PD, compared to those in the health insurance group (HR = 2.466; 95% CI = 1.570-3.875).

Conclusion: In this study, there was no association between long-term PM2.5 exposure and the risk of PD. Age and social economic status were associated with the risk of PD.

To cite this abstract in AMA style:

Y.S Hwang, S.Y Jo, Y.J Kim, K.W Park, S.H Lee, S.J Chung. Long-term effects of air pollution on the risk of Parkinson’s disease [abstract]. Mov Disord. 2020; 35 (suppl 1). https://www.mdsabstracts.org/abstract/long-term-effects-of-air-pollution-on-the-risk-of-parkinsons-disease/. Accessed July 1, 2025.
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

« Back to MDS Virtual Congress 2020

MDS Abstracts - https://www.mdsabstracts.org/abstract/long-term-effects-of-air-pollution-on-the-risk-of-parkinsons-disease/

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Covid vaccine induced parkinsonism and cognitive dysfunction
  • Life expectancy with and without Parkinson’s disease in the general population
  • What is the appropriate sleep position for Parkinson's disease patients with orthostatic hypotension in the morning?
  • Estimation of the 2020 Global Population of Parkinson’s Disease (PD)
  • An atypical and interesting feature of Parkinson´s disease
  • Covid vaccine induced parkinsonism and cognitive dysfunction
  • Life expectancy with and without Parkinson’s disease in the general population
  • What is the appropriate sleep position for Parkinson's disease patients with orthostatic hypotension in the morning?
  • An atypical and interesting feature of Parkinson´s disease
  • Increased Risks of Botulinum Toxin Injection in Patients with Hypermobility Ehlers Danlos Syndrome: A Case Series
  • Movement disorders in chronic obstructive pulmonary disease (COPD); the effect of pulmonary disease to brain
  • Help & Support
  • About Us
  • Cookies & Privacy
  • Wiley Job Network
  • Terms & Conditions
  • Advertisers & Agents
Copyright © 2025 International Parkinson and Movement Disorder Society. All Rights Reserved.
Wiley