Longitudinal Measurements of Glucocerebrosidase activity in Parkinson’s patients and controls: the PPMI study
Objective: To test the correlations between longitudinal measurements of glucocerebrosidase (GCase; encoded by GBA) enzymatic activity and Parkinson’s disease (PD) phenotype in the Parkinson’s Progression…A Fluctuating Qualitative Dermatoglyphic Trait, Dankmeijer’s and Furuhata’s Index as a Risk Marker in Diabetic Parkinson’s Patients of Guyana: A Case-Control Study
Objective: The current study aims to compare and evaluate the fluctuating qualitative dermatoglyphic trait, Furuhata’s and Dankmeijer’s index as a risk marker in Diabetes and…Neurodevelopmental disorder and parkinsonism in a patient with WDR45 variant: a long-term outcome
Objective: To expand the clinical spectrum of WDR45 deficiency. Background: Beta-propeller protein-associated neurodegeneration (BPAN) due to WDR45 defect is a rare X-linked dominant disorder of…Burden of variants in Parkinson’s disease-associated genes in GBA mutation carriers
Objective: The main objective of this study is to examine the burden of variants in genes that are known or suspected to be involved in…Alpha-synuclein and Amyloid beta peptide 1-42 in Parkinson’s disease and parkinsonian plus syndrome cohorts
Objective: To evaluate the serum levels of α-synuclein (α-syn) and Amyloid β 1-42 (Aβ1-42) in the patients of Parkinson’s disease (PD), progressive supranuclear palsy (PSP)…Gut Microbiota in Parkinson’s disease: influences of device-assisted therapies
Objective: To determine the temporal stability of gut microbiota (GM) profiles around the acute establishment of advanced Parkinson's disease (PD) therapies and describe resulting alterations in…Detection of alpha-synuclein aggregation from submandibular and esophageal tissue of patients with synucleinopathies
Objective: Utilize cyclic amplification methods to facilitate detection of aggregation prone forms of a-syn from submandibular or esophageal tissue of patients with syncleinopathies. Background: In…Functional connectivity traits in Parkinson’s disease mild cognitive impairment
Objective: Our objective is to assess functional networks in PD mild cognitive impairment (PD-MCI) and their contribution to global connectivity combining Connectome ICA (connICA) and…Deep learning-based automatic nigrosome 1 segmentation on 3T susceptibility-weighted MRI
Objective: The aim of this study was to develop a deep learning-based system for automatic nigrosome 1 segmentation on susceptibility-weighted imaging (SWI) from 3T magnetic…MRI functional connectivity analysis for speech impairment in Parkinson’s disease
Objective: We aimed to investigate underlying modifications of MRI functional connectivity between dysarthric and non-dysarthric patients with Parkinson’s disease and healthy controls. Background: Altered speech…
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