The main reasons for essential blepharospasm botulinum neurotoxin (BoNT) treatment discontinuation in Latvian population.
Objective: To investigate the effectiveness of BoNT treatment in patients with essential blepharospasm and determine the most common reasons for discontinuation of the treatment. Background: Essential…Spread to a third body site in patients with segmental/multifocal idiopathic adult-onset dystonia
Objective: The aim of the study is to fully characterize the spread of segmental/multifocal dystonia to a third body site in idiopathic adult-onset patients. Background: With…MDSGene systematic review on dopa-responsive dystonia caused by mutations in GCH1, TH, SPR, PTS, or QDPR
Objective: To systematically review information regarding genotype, phenotype, and biochemistry in dopa-responsive dystonia (DRD). Background: To date, five causative genes (GCH1, TH, SPR, PTS, and…MDS Basic Scientists Survey demonstrates Potential for Crosspollination between Basic Scientists and MDS
Objective: The purpose of the survey was to paint a clearer picture of the expectations of basic scientists on how the MDS can strengthen interactions…Racial and ethnic differences in patients with Parkinson’s Disease across Parkinson’s Disease Centers of Excellence
Objective: To investigate treatment, health-related quality of life, and other outcome differences in patients with Parkinson’s Disease (PD) across race and ethnicity. Background: The inclusion…Morbidity and mortality from neurodegenerative patients hospitalized with COVID-19 in the Chicagoland area
Objective: To assess morbidity and mortality of acute COVID-19 infection in hospitalized patients with neurodegenerative diseases and compare with age-matched controls. Background: Outcomes from COVID-19…Significant increase of new pediatric functional movement disorders during the COVID-19 global pandemic
Objective: This study aims to assess the incidence of pediatric Functional Movement Disorders (FMD) during the COVID-19 global pandemic compared to pre-pandemic baseline. Background: Referrals…Automatic and objective speech analysis in Huntington disease
Objective: To investigate the use of digital technology to assess speech in people with Huntington disease (HD). Background: Dysarthria is common in Huntington disease and…Fine-grained prediction of Huntington’s disease stage using a meta-model approach
Objective: We developed a machine learning (ML) framework that facilitates prediction of individual-level Huntington’s disease (HD) stage. The proposed meta-model approach classifies participants according to…Development of the Huntington’s Disease Integrated Staging System (HD-ISS)
Objective: To propose a new HD framework, referred to as the HD-ISS, that comprises an HD biological research definition and evidence-based staging centered on prognostic…
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