Comparison of gastrointestinal transit times in typical and erratic levodopa-responders in patients with Parkinson’s disease.
Objective: To determine if altered transit time in the various segments of the gastrointestinal (GI) tract relates to the variability of clinical responses and serum…Serial olfactory testing for the diagnosis of prodromal Parkinson disease in the Parkinson Associated Risk Syndrome (PARS) study
Objective: To assess whether repeat olfactory testing in initially hyposmic subjects improves prediction of conversion to Parkinson disease (PD). Background: Hyposmia is a common prodromal…Evidence of gut dysbiosis in treatment-naïve de novo Parkinson’s disease
Objective: To determine the gut microbiome composition of treatment-naïve de novo Parkinson’s disease (PD) patients. Background: Over fifteen studies have independently demonstrated gut dysbiosis in…Motor Function Test Protocol for Parkinsonian Triad in Rodent Model of Parkinson’s Disease
Objective: To review motor deficits protocols and create a set of behavioural protocols that critically address the parkinsonian triad's quantification in Parkinson's disease models. Background:…Markers of Parkinson-related impulsive-compulsive behaviors in the activity of single units in the subthalamic nucleus
Objective: To characterize the features of the activity of single neurons of the subthalamic nucleus associated to impulsive-compulsive behaviors (ICBs) in Parkinson’s Disease (PD). Background:…Cellular Modeling of Tyrosine Hydroxylase Deficiency Recapitulates Patient Phenotypes and Response to Treatment.
Objective: Characterize a new cellular model of Tyrosine Hydroxylase deficiency (THD) based on induced pluripotent stem cells (iPSCs) to better understand the pathophysiology and test…Medication effects and validity of home-based freezing tests in Parkinson’s disease
Objective: Determine the validity of a ‘freezing-provoking protocol’ (FOG-PP) in the home setting and assess the effects of medication on freezing of gait (FOG) during…FEASIBILITY OF THE HOME-BASED DANCE EXERCISE FOR ADULTS WITH MODERATE PARKINSON’S DISEASE – A PILOT STUDY CASE REPORT
Objective: To explore the feasibility of a home-based dance exercise for adults with moderate Parkinson’s Disease (PD) on balance, functional mobility, quality of life (QOL),…Exercise habits of People with Parkinson’s across different ethnic populations
Objective: To investigate exercise habits across different ethnicities of People with Parkinson’s. Background: There is evidence that exercise is beneficial for People with Parkinson’s (PwP)…Development of a remote physical exercise program during COVID-19 pandemic for individuals with Parkinson’s disease
Objective: To describe the development process of adaptation of in-person physical exercise program to telemonitoring format to people with Parkinson’s disease (PD). Background: People with…
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