Proof-of-concept study testing bevantolol (SOM3355) as treatment of chorea in Huntington’s disease
Objective: Proof-of-concept phase IIa study assessing bevantolol (SOM3355) efficacy and safety in reducing chorea in Huntington’s disease (HD). Background: Bevantolol hydrochloride, a β1‐adrenoceptor antagonist used…The Huntington’s Disease Structured Interview of Function (HD-SIF): A remotely administered caregiver interview for later stage HD
Objective: To create structured interviews for the UHDRS ’99 functional scales that can be remotely administered to caregivers of Huntington’s disease gene expansion carriers (HDGECs)…Lance-Adams Syndrome: A case series in El Salvador
Objective: To describe the clinical presentation and response to treatment of cases of Lance-Adams Syndrome in a Movement Disorders Clinic in El Salvador. Background: Lance-Adams…Visualising tau in patients with progressive supranuclear palsy using PI2620-PET
Objective: This study investigates the use of a new tau-specific PET radiotracer, [18F]-PI-2620, as a tool for visualising tau in the living brain. Background: The…Pallidal recordings in fully implanted dystonic patients: preliminary results
Objective: To describe oscillatory patterns of pallidal local field potentials (LFP) in fully implanted patients with dystonia. Background: New implantable devices for deep brain stimulation…How can patients’ trajectories inform the co-design of an integrated care network for people living with Parkinson’s Disease?
Objective: The aim of this study is to provide a better understanding of how patients’ experience could inform the design of an integrated care network…Alpha-synuclein oligomers detection by proximity ligation assay in skin biopsy is a biomarker for Parkinson’s disease
Objective: To assess the presence of oligomeric alpha-synuclein (αSyn), an early pathogenic species, in skin nerve fibers of patients with Parkinson’s disease (PD) and atypical…The alien hand syndrome
Objective: This case is presented to create awareness of this interesting clinical scenario, which can be terrifying to the patients and confusing to the physicians…Feasibility of Instituting Graduated High intensity Training (FIGHT-PD); Protocol for a non-contact boxing exercise study
Objective: 1. To determine the feasibility and logistics of conducting a non-contact boxing exercise program for PD patients. 2. To determine the tolerability of the…Long-Term Safety and Efficacy of Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease
Objective: Evaluate long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL) for on-demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD).…
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