MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Precision Medicine in Neurodegeneration associated with Pantothenate kinase (PKAN) , its possible?

    J. Abril Jaramillo (Seville, Spain)

    Objective: The objective of this review is to open a discussion on the usefulness of the use of cell models derived from patients as a…
  • MDS Virtual Congress 2021

    Palliative care evaluation for movement disorders during COVID-19: Using Tele neurology to provide real-time care for an at risk Veterans Population.

    N. Hack, K. Dalton (Rockville, USA)

    Objective: To deliver palliative care via telemedicine in a video format to veterans at risk with movement disorders in need of palliative care in the…
  • MDS Virtual Congress 2021

    The OCEAN (OpiCapone Effect on motor fluctuations and associated pAiN) study in Parkinson’s disease: design and rationale of a randomized double-blind placebo-controlled trial

    K. Chaudhuri, P. Odin, J. Ferreira, A. Antonini, O. Rascol, M. Kurtis, A. Storch, K. Bannister, R. Costa, D. Magalhães, J. Rocha, P. Soares-da-Silva (London, United Kingdom)

    Objective: To evaluate if treatment with opicapone (OPC) in patients with Parkinson’s disease (PD) improves pain related to end-of-dose fluctuations, consequently improving patients’ well-being. Background:…
  • MDS Virtual Congress 2021

    Overcoming clinical research challenges during a pandemic: selection and implementation of digital phenotyping solutions in a natural history study of G2019S LRRK2 Parkinson’s disease.

    N. France, C. Tomkins-Lane, M. Maurer, C. Barlow, E. Davies, C. Matthews, A. Palozoglu, L. Farid (South San Francisco, USA)

    Objective: To identify candidate wearable devices or digital solutions suitable for conducting the Timed Up and Go (TUG) test and evaluate real-world performance remotely during…
  • MDS Virtual Congress 2021

    The Effects of Telepractice- Based LSVT-BIG Training in Patients with Parkinson’s Disease in Covid-19 pandemic: Preliminary Results

    G. Kaya Aytutuldu, B. Ersoz Huseyinsinoglu, N. Karagoz Sakalli, A. Sen (İstanbul, Turkey)

    Objective: To investigate the effects of telepractice-based LSVT-BIG training on balance and mobility parameters in patients with Parkinson’s Disease (PD). Background: Patients with PD who…
  • MDS Virtual Congress 2021

    Parkinson Progression Marker Initiative – New Science/New Cohorts

    K. Marek, A. Siderowf, T. Simuni, L. Chahine, K. Kieburtz, B. Mollenhauer, D. Galasko, K. Merchant, E. Brown, C. Coffey, R. Dobkin, T. Foroud, K. Poston, E. Flagg, S. Chowdhury, C. Tanner (New Haven, USA)

    Objective: The Parkinson Progression Marker Initiative (PPMI) is expanding its cohorts and exploring additional biomarkers of PD progression to test hypotheses of the underlying molecular…
  • MDS Virtual Congress 2021

    IMPACT OF STANDARD-OF-CARE MEDICATIONS ON TIME-OFF READOUTS IN CLINICAL TRIALS. A QUANTITATIVE SYSTEMS PHARMACOLOGY APPROACH

    R. Rose, E. Mitchell, H. Geerts (Sheffield, United Kingdom)

    Objective: To mitigate clinical variability of Time-Off with various therapeutic combinations Background: There is increasing interest to use wearable-based digital health measures to continuously monitor…
  • MDS Virtual Congress 2021

    Unilateral Subthalamic Versus Unilateral Pallidal Stimulation in Parkinson’s Disease: A Randomized Double-Blind Crossover Study

    ZT. Zeng, LB. Wang, WK. Shi, ZY. Lin, BM. Sun, CC. Zhang, DY. Li (Shanghai, China)

    Objective: To compare the acute effects of deep brain stimulation (DBS) of unilateral subthalamic nucleus (STN) and unilateral globus pallidus interna (GPi) on motor function…
  • MDS Virtual Congress 2021

    The early post-transplant period in Parkinson’s disease: the low intravenous dose effect.

    V. Chyzhyk, V. Ponomarev, N. Aleinikava, A. Boika, M. Zafranskaya, D. Nizheharodava (Minsk, Belarus)

    Objective: To compare the early results of the introduction of MSCs via different routs of administration on the dynamics of the motor symptoms in patients…
  • MDS Virtual Congress 2021

    Global access to Parkinson’s disease treatment

    JLY. Cheong, ZHK. Goh, C. Marras, C. Tanner, M. Kasten, A. Korczyn, L. Chahine, R. Lo, A. Noyce (London, United Kingdom)

    Objective: To examine the availability of PD treatment by country, and analyse differences by national income as defined by the World Bank (high income countries…
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