Next-generation sequencing of plasma-associated extracellular vesicle miRNAs as potential biomarkers for Parkinson’s disease and its prodromal stage
Objective: This study aimed to identify subsets of plasma EV-associated miRNAs with diagnostic potential for PD and iRBD, the prodromal stage of PD. Background: Parkinson’s…Metabolic alterations in a Drosophila model of Parkinson’s disease
Objective: Identification of metabolic alterations that could be contributing to Parkinson’s disease (PD) physiopathology and become new biomarkers or therapeutic targets for the disease. Background:…Distinct memory networks in Parkinson’s disease (PD) and Alzheimer’s disease (AD): Effects of APOE
Objective: As part of the Ontario Neurodegenerative Disease Research Initiative, we investigated group differences in functional connectivity within two distinct memory networks: posterior medial network…Striatal dopaminergic loss in early clinically unilateral Parkinson’s disease: a systematic review
Objective: To quantify the extent of dopaminergic loss in early clinically unilateral PD from studies using presynaptic dopamine imaging with either single photon emission computed tomography…Characteristics of the amyloid beta networks in Parkinson’s disease patients: a PPMI study
Objective: The impact that amyloid beta (Aβ) accumulation in the brain has on the progression of Parkinson’s disease (PD) pathology is complex and poorly understood…The Influence of Affective Priming on the Speech Production Network in Parkinson’s Disease
Objective: Examine Parkinson’s disease (PD) related changes in the speech production network (SPN) and its reaction to emotional distraction. Background: PD can cause speech alterations…Neuroanatomical signatures of genetic risk for Parkinson’s Disease in healthy adults
Objective: To determine whether there is a relationship between genetic risk for Parkinson’s disease (PD) and brain structure in healthy adults. Background: PD pathology begins…Inter-Electrode Distance Influences the Spectral Power of Subthalamic Bipolar Local Field Potentials Recordings in Parkinson’s Disease
Objective: This study aimed to evaluate spectral dissimilarities and their correlations with clinical symptoms of intra-operative local field potentials (LFP) acquired from wide- and close-spaced…Early Adapter: Study Protocol for the Multi-Center Post-Market Study of Adaptive Deep Brain Stimulation (aDBS) in Japan
Objective: To assess the procedures for introducing two adaptive deep brain stimulation (aDBS) modes (single and dual threshold) in Parkinson’s disease patients (PD) in a…Autonomic Symptoms as Predictors of Quality of Life in Parkinson’s Disease: A 5-year follow up study
Objective: The aim of this study was to investigate whether the autonomic symptoms could predict the quality of life of patients with PD. Background: Parkinson's…
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