MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Home Health Management of Parkinson’s Disease Deep Brain Stimulation: A Randomized Clinical Trial

    G. Duffley, A. Wright, C. Hess, A. Ramirez-Zamora, P. Zeilman, S. Chiu, A. Szabo, B. Lutz, K. Foote, M. Okun, C. Butson (Salt Lake City, USA)

    Objective: Evaluate the efficacy of home health DBS postoperative management in an effort to reduce travel burden and improve access. Background: The travel required to…
  • MDS Virtual Congress 2021

    Should Amantadine DR/ER Be Considered Prior to Device-Aided Therapies for Parkinson’s Disease?

    R. Hauser, S. Goud, A. Formella (Tampa, USA)

    Objective: Evaluate delayed release/extended release amantadine (AMT DR/ER) capsules for motor complications in patients meeting 5-2-1 criteria for device-aided therapies (DAT) in advanced Parkinson disease.…
  • MDS Virtual Congress 2021

    CVT-301 (levodopa inhalation powder): meta-analysis of safety in patients with Parkinson’s disease (PD)

    P. Lewitt, P. Zhao, A. Corbin, D. Kegler-Ebo, B. Blank (West Bloomfield, USA)

    Objective: Safety results from a phase 3, double-blind study of CVT-301 in patients with PD were combined with results from a 4-week, phase 2b, double-blind,…
  • MDS Virtual Congress 2021

    Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease: Characterization of Acute Nausea During Dose Titration

    W. Ondo, R. Hauser, A. Bowling, S. Isaacson, E. Pappert, B. Navia (Houston, USA)

    Objective: Characterize acute episodes of nausea experienced by patients with Parkinson’s disease (PD) receiving apomorphine sublingual film (APL) for the on-demand treatment of “OFF” episodes.…
  • MDS Virtual Congress 2021

    Impulse Control Disorders Following Bilateral Subthalamic Deep Brain Stimulation for Parkinson’s Disease: The INTREPID Randomized Controlled Trial

    T. Stiep, A. Ramirez-Zamora, A. Tröster, R. Jain, L. Chen, M. Okun (Gainesville, USA)

    Objective: To assess frequency and outcomes of impulsivity in study participants receiving bilateral subthalamic deep brain stimulation (STN-DBS) for treatment of Parkinson’s Disease (PD) who…
  • MDS Virtual Congress 2021

    CLE-600: Treating nocturnal and early morning OFF symptomology in Parkinson’s disease with the OLAR® platform

    E. Berkovich (Petch-Tikva, Israel)

    Objective: Development of a treatment for nocturnal and early morning OFF symptomology in Parkinson’s disease. Background: Levodopa Parkinson’s disease (PD) treatment is limited by its…
  • MDS Virtual Congress 2021

    The PD-1102 trial in advanced Parkinson’s disease: safety and clinical outcomes from a 3-year phase 1b study of AADC gene therapy administered via a posterior approach

    S. Factor, R. Gross, A. van Laar, C. Christine, P. Larson, S. Kostyk, R. Lonser, E. Fine, O. Kwhaja, C. Li, A. Meier, G. Liang, E. Roberts, R. Richardson (Atlanta, USA)

    Objective: To present 3-year safety and clinical outcome data from a phase 1b, open-label trial of VY-AADC01 (NBIb-1817) for Parkinson’s disease (PD) patients with motor…
  • MDS Virtual Congress 2021

    Effectiveness of opicapone in Parkinson’s disease patients with motor fluctuations according to baseline use of entacapone: findings from the real-world OPTIPARK study

    W. Jost, H. Reichmann, A. Lees, D. Marinho, D. Magalhães, J. Rocha, P. Soares-da-Silva (Wolfach, Germany)

    Objective: This post-hoc analysis evaluated the effectiveness of opicapone (OPC) in Parkinson’s disease (PD) patients with motor fluctuations (MF) according to baseline use of entacapone…
  • MDS Virtual Congress 2021

    OPTIMIPARK Questionnaire:a tool to optimize treatment in Parkinson´s disease.

    J. Máñez-Miró, F. Vivancos-Matellano, L. Vela-Desojo, R. Martinez-Fernandez, F. Alonso-Frech, N. Lopez-Aristegui, E. Balaguer-Martínez, J. Martinez-Castrillo, L. Lopez-Manzanares, P. Martínez-Martín (Madrid, Spain)

    Objective: To validate the OPTIMIPARK questionnaire as a tool to help the clinician in the adjustment of dopaminergic treatment in Parkinson´s disease(PD). Background: At early…
  • MDS Virtual Congress 2021

    Effectiveness of opicapone in Parkinson’s disease patients with motor fluctuations according to baseline use of safinamide: findings from the real-world OPTIPARK study

    N. Pavese, A. Lees, H. Reichmann, D. Martins, D. Magalhães, J. Rocha, P. Soares-da-Silva (Newcastle Upon Tyne, United Kingdom)

    Objective: This post-hoc analysis evaluated the effectiveness of opicapone (OPC) in Parkinson’s disease (PD) patients with motor fluctuations (MF) according to baseline use of safinamide…
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