Cortical microstructural alterations are more sensitive than morphology changes to cortical degeneration in Parkinson’s disease with mild cognitive impairment
Objective: To compare the sensitivity of detection cortical degenerative changes in patients with Parkinson’s disease (PD) and mild cognitive impairment (MCI) between the diffusion magnetic…An Eyes-Open/Closed Manipulation Reveals Disrupted Default Mode Network Connectivity in Parkinson’s Disease and REM Sleep Behavior Disorder
Objective: To spatially localize disruptions in default mode network connectivity in prodromal and diagnosed Parkinson’s disease relative to controls. Background: Previously our research team reported…Tractography Analysis of the Pedunculopontine Nucleus Correlates with Gait Impairment in Parkinson’s Disease
Objective: Our objective was to correlate pedunculopontine nucleus (PPN) connectivity with quantitative gait metrics in Parkinson’s disease (PD) using diffusion tensor imaging (DTI). Background: Gait…Relationship Between Hyposmia and Olfactory Network Connectivity in Patients With Parkinson’s Disease
Objective: To examine resting-state functional Magnetic Resonance Imaging in a group of Parkinson’s Disease patients, used to characterize changes in functional connectivity of the olfactory…Altered Resting-state Neural Activity in Parkinson’s Disease with Depression: a controlled study based on original meta-analysis results
Objective: Depression is a common non-motor symptom in Parkinson’s disease (PD), while its underlying pathophysiology remains unclear. Previous functional magnetic resonance imaging (fMRI) studies reported…Changes in the cerebellar activity during task based and resting state fMRI in Parkinson’s disease patients with mild cognitive impairment
Objective: To investigate possible brain markers for PD-MCI by undertaking cognitive task-based and resting-state fMRI. Background: Parkinson’s disease (PD) is widely recognised as a movement…The aperiodic component of cortical Local Field Potentials is affected in Parkinson’s Disease and Essential Tremor.
Objective: Characterize the pathophysiology of Parkinson’s Disease (PD) and Essential Tremor (ET) in terms of cortical and subcortical aperiodic neural activity. Background: Classical analysis of…Distinct oscillatory fingerprints in dyskinesias mediated by D1 versus D2 receptors
Objective: To characterize the patterns of cortico-basal ganglia oscillations induced by D1 or D2 receptor agonists in a rat model of L-DOPA-induced dyskinesia. Background: In…ON/OFF Blood Pressure Fluctuation in Parkinson’s Disease
Objective: To examine ON and OFF blood pressure (BP) fluctuations in Parkinson’s Disease (PD) patients. Background: The current practice often is to treat transient hypertensive…Leg muscle contractions compensate for declining cardiac baroreflex in PD Patients
Objective: To investigate if impairments in muscle contraction affects blood pressure (BP) regulation in PD. Background: Orthostatic hypotension (OH) contributes to unexpected falls in PD.…
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