Neuropsychological correlates of Cognitive fluctuations in dementia with Lewy bodies
Objective: To examine which neuropsychological characteristics are associated with cognitive fluctuations (CF) in patients with dementia with Lewy bodies (DLB). Background: СF are core diagnostic…Physical activity and incidence of Parkinson’s disease in French women from the E3N cohort study
Objective: To examine the association between time-dependent physical activity (PA) and incidence of Parkinson’s disease (PD) in women from the E3N cohort over 29 years…Expectations of DBS: the patient’s perspective
Objective: To examine the evolution and change of the treatment-related expectations of patients with advanced Parkinson’s Disease (PD) before and during treatment with bilateral deep…Quality of Life and Motor Outcomes for Parkinson’s Disease Patients 12 Months After Deep Brain Stimulation in China
Objective: Demonstrate improvement in Parkinson’s disease (PD)-related quality of life (QoL) for Deep Brain Stimulation (DBS) patients in a prospective, multicenter study conducted in China.…Unraveling the Potential of Specialized Allied Health Therapy in Parkinson’s Disease
Objective: To investigate discipline-specific effects of specialized Allied Health Therapy on the incidence of Parkinson’s Disease (PD)-related complications. Background: Specialized physiotherapy has been shown to…Effect of the mGlu2/3 orthosteric agonist LY-404,039 on dyskinesia, psychosis-like behaviours, and parkinsonism in the MPTP-lesioned marmoset
Objective: To assess the effect of LY-404,039 on dyskinesia, psychosis-like behaviours (PLBs) and parkinsonism in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset model of Parkinson’s disease (PD). Background:…Antidyskinetic Effects of CaV1.3 Calcium Channel Gene Silencing in Aged Male and Female Parkinsonian Macaques
Objective: To determine whether striatal CaV1.3 gene silencing ameliorates levodopa-induced dyskinesias (LID) in the preclinical gold-standard non-human primate (NHP) model without altering levodopa’s antiparkinsonian benefit.…Pilot case on the use of transcranial pulsed current stimulation(tPCS) in a patient with cervical dystonia(CD)
Objective: To demonstrate the efficacy of tPCS on a patient with CD Background: CD is a common adult-onset dystonia. Abnormal sensorimotor integration and maladaptive plasticity…Correlation between 3 Tesla Brain MRI Nigrosome-1 imaging and SPECT 123I-Ioflupane in parkinsonian disorders
Objective: To correlate nigrosome-1 (NG1) imaging and SPECT 123I-Ioflopane findings to determine the feasibility and diagnostic value of NG1 imaging in a real-world clinical setting.…Motor-Related and Cognition-Related Safety of Pimavanserin in Patients with Parkinson’s Disease Psychosis (PDP)
Objective: Evaluate motor- and cognition-related safety in pimavanserin-treated patients with PDP. Background: Pimavanserin, a selective 5-HT2A inverse agonist/antagonist, is the only US FDA-approved treatment for…
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