Reliability of brainsense technology as compared to SoC in STN DBS programming
Objective: We aimed to study coincidence between the contact selected at programming session by experienced neurologists at 6months follow up after bilateral STN DBS (considered…Neuroimaging correlates of postural instability in motor subtypes of Parkinson’s disease
Objective: In this study, we aimed to identify the brain structures associated with postural instability (PI) in Parkinson’s disease (PD) subtypes using different MRI approaches. Background:…Bilateral subthalamic nucleus deep brain stimulation in Parkinson’s disease: preoperative predictors of speech worsening
Objective: To find preoperative predictive factors of short-term postoperative speech worsening in a large cohort of consecutive PD patients treated with bilateral STN-DBS. Background: Subthalamic…A novel truncating variant in UBAP1 gene causing hereditary spastic paraplegia type 80
Objective: To describe a novel truncating variant in UBAP1 gene in a first Malay population, and expand the genotype and phenotype. Background: Hereditary Spastic paraplegia…Nucleus basalis of Meynert and total gray matter atrophy are related to cognitive and gait decline in Parkinson’s disease
Objective: To assess the associations between the nucleus basalis of Meynert (NBM) and total grey matter atrophy with cognitive phenotype and gait measures in a…PET visualization of α-synuclein pathologies in humans using [18F]C05-05
Objective: This study aimed to visualize α-synuclein aggregates in living patients with Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA).…Differences in gray matter atrophy and functional connectivity between motor subtypes of Parkinson’s disease
Objective: This study compared gray matter volume (GMV) and functional connectivity among patients with Parkinson’s disease involving postural instability/gait difficulty (PD-PIGD), patients with tremor-dominant Parkinson’s disease (PD-TD) and healthy…Clinical and functional determinants of motor reserve in patients with de novo Parkinson’s disease
Objective: To determine the clinical determinants and the role of serotonergic innervation on motor reserve in patients with de novo Parkinson's disease. Background: Patients with…Bilateral staged MR-guided focused ultrasound thalamotomy for Essential Tremor: one-year follow-up results
Objective: To evaluate the safety and efficacy outcomes of bilateral staged magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy for medication-refractory essential tremor (ET) and ET…Effectiveness of speech therapy in patients with Parkinson’s disease – a randomized controlled trial
Objective: We aimed to assess the effectiveness of speech therapy on improving quality of life and speech quality in patients with Parkinson’s disease. Background: Although…
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