Clinical toolkits to improve conversations about Parkinson’s dementia
Objective: To co-produce, with people living with Parkinson’s and professionals, a pair of toolkits to improve conversations about Parkinson’s dementia in the clinic: one for…Thymoquinone and Edible Bird Nest: The Secret Ingredients to Protect Against MPTP-induced zebrafish Parkinson’s disease
Objective: Objectives: to create and validate an MPTP neurotoxin-based zebrafish model of Parkinson's disease and explore the therapeutic potential and neuroprotective effects of thymoquinone and…Prevalence of cardiovascular drugs and oral anticoagulants use among persons with and without Parkinson’s disease
Objective: We investigated prevalence of Cardiovascular drugs and Oral anticoagulants (OAC) use among community-dwelling persons with and without Parkinson's disease (PD) in relation to PD…Glycated alpha-synuclein and it emerging role in early onset of Parkinson’s disease
Objective: To elucidate, the molecular mechanism underlying glycated α-Syn mediated dopaminergic (DAergic) neurodegeneration in the substantia nigra (SN) via the AGE/RAGE signaling pathway. Background: Intracytoplasmic…Parkinson’s disease (PD) progression is associated with past exposure to organic contaminants in water at Marine Corps Base Camp Lejeune
Objective: To test whether PD progression is more rapid in individuals who were exposed to volatile organic compounds in the water supply at Camp Lejeune…Age-associated changes in the striatal proteins in aging Asian-Indians
Objective: To examine the age-related changes in tyrosine hydroxylase (TH), vesicular monoamine transporter2 (VMAT2), post-synaptic density protein-95 (PSD-95) and dopamine receptors (D1R, D2R) expression in the…An evaluation of NBI-827104 for essential tremor: results from a randomized, double-blind, placebo-controlled, dose-escalation, crossover study
Objective: To evaluate the efficacy of NBI-827104 in patients with essential tremor (ET). Background: NBI-827104 is a T-type calcium channel blocker that demonstrated tremorolytic activity…Clinical Prediction of GBA Carrier Status in Parkinson’s Disease
Objective: To design a model for prediction of GBA carrier status based on clinical and demographic features in a cohort of PD patients. Background: Given…Bilateral Globus Pallidus Internus Deep Brain Stimulation for Cervical Dystonia: Effects on Motor and Non-Motor Symptoms within 5 Years Follow Up
Objective: This study firstly aims to measure the efficacy of GPi-DBS on motor and non-motor symptoms of CD. A secondary aim was to evaluate if…using latent class mixed modelling to profile Parkinson’s disease patients at risk of cognitive decline
Objective: To determine the clinical profile of cognitive subtypes in Parkinson's disease (PD) based on their rate of change in global cognitive ability over time.…
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