Bone Health in Parkinson’s Disease
Objective: Optimise bone health in people with Parkinson’s Disease Background: People with Parkinson’s Disease (PD) have an increased risk of osteoporosis and associated fractures due…Late onset cerebellar ataxia in patients treated with VIM DBS
Objective: To highlight the predictors for onset of cerebellar ataxia in patients treated with deep brain stimulation (DBS) of the Thalamic Ventral Intermediate Nucleus (VIM)…Mitochondrial DNA copy number is associated with the severity of motor symptoms and dementia in Parkinson’s disease
Objective: We aimed to investigate the diagnostic and prognostic role of blood mitochondrial DNA copy number (mtDNA-CN) measured by whole genome sequencing (WGS) in relation…Exploring the effects of torsinA dysfunction in an iPSC-derived neuronal model of TOR1A dystonia
Objective: To investigate phenotypic differences between iPSC-differentiated cortical neurons derived from patients with TOR1A dystonia compared to healthy controls. Background: Primary generalised dystonia is most…Online education to promote compensation strategies for gait impairments in underserved Parkinson populations
Objective: Here, we explore the potential health benefits of using an online educational platform about compensation strategies for gait impairment in Parkinson’s disease (PD), in…How does a diagnosis of Dementia with Parkinson’s influence future care provision?
Objective: To describe the trajectory of Parkinson’s after the onset of dementia including setting of care, frailty levels and mortality rate. Background: Cardiff and Vale…Trial site factor in Parkinson’s disease (PD) diary non-compliance
Objective: In this analysis, we wanted to explore if PD diary non-compliance is distributed randomly in the dataset or if it has a tendency to…Epidemiology of late-onset Parkinson’s disease in least-developed to Upper Middle-Income Countries: A Systematic Review and Meta-analysis
Objective: To conduct a meta-analysis of the epidemiological studies of Parkinson's disease (PD) performed in populations from least-developed to upper-middle-income countries. Background: While several epidemiology…Association between Parkinson’s Disease and Atrial Fibrillation: A Literature Review
Objective: Our literature review aims to summarize what has been reported in the literature with the next steps of looking at Kaiser Permanente (KP) to…Neurofilament light chain, tau-PET and microglia-PET predict clinical progression in amyloid-negative corticobasal syndrome
Objective: A head-to-head comparison of neuroimaging (tau-PET, microglia-PET, structural MRI) and plasma biomarker Neurofilament light chain (NfL) as prognostic tools for longitudinal clinical trajectories in…
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