Device-aided Recording of Gait Parameters and Motor Fluctuations in Patients with advanced Parkinson’s disease in the Home Environment
Objective: To objectively assess mobility and gait parameters in the ON and OFF state in patients with advanced Parkinson's disease (PD) under everyday conditions using…Enhancing iRBD diagnosis through 2D video analysis: a machine learning approach
Objective: Evaluate the performance of a classifier using computer vision trained on video-polysomnography (vPSG) data recorded in the sleep laboratory setting over a single night…A 3D CNN Approach for the Classification of Multiple System Atrophy using Multimodal Multicentric MRI
Objective: To automatically distinguish between healthy controls (HC) and patients with multiple system atrophy (MSA) with a completely automatic approach using a 3D convolutional neural…Treatment Patterns and Comorbidities Associated with Multiple System Atrophy: A Comparative Study
Objective: To examine comorbidities and co-medications in patients with multiple system atrophy (MSA) compared to a matched-control in real-world setting Background: Currently MSA is managed…Development and Validation of a Clinical Scale for Distinguishing Multiple System Atrophy from 4-Repeat Tauopathies
Objective: We aimed to develop a clinical scale that distinguishes between Multiple System Atrophy (MSA) and 4-repeat tauopathies (4RT: CBD, PSP) using a standardized neurological…Frequency of Falls as a Presenti̇ng Symptom and Its Effect i̇n Prognosi̇s i̇n Progressi̇ve Supranuclear Palsy
Objective: We aimed to evaluate frequency of falls as a presenting symptom and its effect on prognosis in PSP patients. Background: Progressive supranuclear palsy is…Unveiling the Link: Insulin’s Novel Role in Modulating α-Synuclein Accumulation in Parkinson’s Disease
Objective: This study marks the inaugural attempt to investigate the direct effects of insulin on pathological α-synuclein accumulation induced by the addition of α-synuclein preformed…Utilization of Skin Punch Biopsy for the Diagnosis of Alpha-synucleinopathy in Clinical Practice
Objective: To understand the use of skin punch biopsies for diagnosis and management of α-synucleinopathy within a large medical system. Background: Skin punch biopsy has…Increased cholinergic activity in specific brain regions associated with the presence of dyskinesias in Parkinson’s disease: A [18F]-FEOBV PET study
Objective: To explore the role of cholinergic dysfunction in dyskinesia symptoms in people with Parkinson’s disease (PD). Background: Dyskinesias, involuntary and sometimes excessive or uncontrolled…Clinical Profile of Motor Complications in Parkinson’s Disease Patients at A National Tertiary Hospital In Indonesia
Objective: To analyse factors associated with motor complications in Parkinson's disease at a national tertiary referral hospital in Indonesia. Background: As Parkinson's disease progresses, levodopa…
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