Multifaceted Challenges in Multisystem Atrophy Management: Medication Sensitivity, Emotional Lability, and Increased Fall Risk
Objective: Multisystem atrophy (MSA) epitomizes a formidable quandary within neurological and geriatric disciplines, delineated by complex manifestations encompassing autonomic dysfunction, parkinsonism, and cerebellar ataxia. This…Multiple System Atrophy in a Patient with Normal Pressure Hydrocephalus
Objective: To review a case of a patient diagnosed with both NPH and MSA. Background: Multiple system atrophy (MSA) is a progressive neurodegenerative disease that…Dermal 4R-Tau seeding as a novel biomarker for Progressive Supranuclear Palsy
Objective: To ascertain the presence of misfolded tau species in the skin of Progressive Supranuclear Palsy (PSP) patients and evaluate its utility as a potential…Video-oculography for enhancing the diagnostic accuracy of early oculomotor dysfunction in Progressive Supranuclear Palsy
Objective: To test (1) the role of video oculography (VOG) in the detection of slow saccades in two common subtypes of Progressive Supranuclear Palsy (PSP)…Remote Digital Longitudinal Assessment of Speech, Fluency and Cognitive Function in Progressive Supranuclear Palsy
Objective: To conduct a comparative analysis of remote digital assessment methods for evaluating speech, fluency, and cognitive function in individuals diagnosed with Progressive Supranuclear Palsy…Prediction of amyloid positivity in Dementia with Lewy bodies using the early-phase 18F-FP-CIT PET images
Objective: This study aims to explore whether early-phase 18F-N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (18F-FP-CIT) positron emission tomography (PET) images can predict β-amyloid positivity on 18F-florbetaben (18F-FBB) PET scans…Identification of Novel Blood Biomarkers among Data-Driven Parkinson’s Disease Clusters in Asian Populations
Objective: The aim of this study is to explore the correlation between emerging serum biomarkers and subtypes of Parkinson's disease (PD). Background: PD is a…α-Synuclein Pathology Across Movement Disorders and Neurodegenerative Diseases by Seed Amplification Assay
Objective: To assess the frequency of pathological α-synuclein (αSyn) in various movement disorders and neurodegenerative diseases from a specialized movement disorder clinic by αSyn seed…Assessing Feasibility of Using Phone Video Data in Diagnosing Parkinsonism
Objective: This project aims to address potential gaps in rural healthcare by assessing the feasibility of using mobile phone data to identify features of parkinsonism…Mixed Brain Pathology in Neurodegenerative Parkinsonism and Dementia
Objective: To assess the presence of mixed neurodegenerative pathology and its proportion in the prospective cohort of patients treated for any phenotype of neurodegenerative parkinsonism,…
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