Nasal septum deviation correlates with asymmetry in Parkinson’s disease
Objective: To assesse whether asymmetry in the nasal cavity is related to dopaminergic dysfunction asymmetry in PD patients Background: Asymmetry in motor dysfunction and associated dopaminergic…Objective Monitoring of Axial symptoms in Parkinson’s Disease (OMNIA-PARK): the Study Protocol.
Objective: This study aims to develop and validate a technological set up for the objective assessment and continuous monitoring of axial symptoms in Parkinson’s Disease…Increase eye blink rate as a motor fluctuation in levodopa-Induced dyskinesia in parkinson’s disease a forgotten indicator of motor fluctuations a case report
Objective: To recognize the increase eye blink rate (EBR) as a potential motor fluctuation (MF) in a PD patient undergoing levodopa treatment Background: A normal…Parkinson’s disease GWAS-linked SNCA carriers show slower non-motor and cognitive progression
Objective: To investigate the disease progression between SNCA rs6826785 C allele carriers and noncarriers over 5 years. Background: A genome-wide association study-linked variant (SNCA rs6826785) was shown to have…Parkinson’s Disease Epidemiology and Treatment Characteristics in Australia
Objective: This project aims to identify epidemiological characteristics specific to people diagnosed with Parkinson’s disease (PD) treated with PD medications or device-aided therapies in New…A Registry for Sleep and Circadian Health Quality in Parkinson’s Disease (ReSCQu-PD)
Objective: To characterize sleep-, circadian- and disease-related factors contributing to daytime sleepiness in a cohort of people with Parkinson’s Disease (PwPD). Background: Excessive daytime sleepiness…Differential Effect of alpha-Synuclein on Mitochondrial Morphology in PD and MSA
Objective: In this study, we investigated the morphology of mitochondria and localization of alpha-synuclein as driven by alpha-synuclein isolated from PD and MSA brain-derived tissue.…Neuronal DJ-1 regulates microglia activation via ADAM10-mediated CX3CL1 secretion
Objective: DJ-1, also known as Parkinson's disease protein 7 (PARK7), is a multifunctional protein that is important in regulating oxidative stress and neuroprotection. Background: The…Apolipoprotein E ɛ4-allele and Amygdala Atrophy in Parkinson’s Disease: A Preliminary Longitudinal Analysis from the ONDRI Cohort
Objective: To investigate the association of apolipoprotein E ɛ4-allele (APOE-ε4) with amygdala volumes longitudinally in Parkinson’s disease (PD). Background: APOE-ε4 is a genetic risk factor…Unveiling the Molecular Mechanism of Polydatin in Ameliorating Parkinson’s Disease via the DRD2/CRYAB/NF-κB Axis in Astrocytes and Exploring Cell Therapy Strategies
Objective: Define polydatin's therapeutic mechanism targeting astrocyte-mediated neuroinflammation in Parkinson's disease (PD) and assess combinatorial efficacy with dopamine progenitor transplantation. Background: PD progression involves substantia…
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