Dietary and Environmental Risk factors of Parkinson’s Disease: An integrated study combining Network Pharmacology and Molecular Docking Analyses
Objective: This large-scale case-control study using network pharmacology and molecular docking, aimed to identify dietary and environmental risk factors of Parkinson’s disease (PD). Background: PD…Effectiveness of Light Touch Support Device in Assisting Activities of Daily Living: A Pilot Study
Objective: To evaluate the effectiveness of a pneumatic actuator to assist Parkinson's disease patients in daily life activities. Background: Parkinson's disease patients may face difficulty…Using Chronic DBS Brain Sensing Data to Develop an AI-based Engine for Clinical Insights
Objective: Our aim is to build an AI-based algorithm engine to deliver brain sensing-based data insights from deep brain stimulation (DBS) therapy systems that are…Examining Disparities and Device Usage in Outpatient Telemedicine Visits Amongst Movement Disorders Patients
Objective: To characterize trends in device usage (mobile-device vs. personal computer (PC)) across demographic factors for video-based telemedicine visits in an urban tertiary Movement Disorders…Time for a digital clock?
Objective: Evaluate an automated digital tool for administering and scoring the Clock Drawing Test (CDT) in a movement disorders clinic. Background: The CDT is a…Leveraging Duty-cycle Based Programming for Deep Brain Stimulation
Objective: Provide a review of duty-cycle based programming, also referred to as “cycling” (CycPm), and its potential role in DBS for movement disorders. Background: Continuous…The Syn-D Study: Detection of Cutaneous Phosphorylated Alpha-Synuclein and blood P-Tau 217 in Patients with Mild Cognitive Impairment
Objective: To quantify the deposition of cutaneous P-SYN and blood P-Tau 217 in patients with suspected DLB and AD at the mild cognitive impairment (MCI)…Parkinsonism in KMT5B-related Disorders: Expanding the Spectrum.
Objective: To describe a novel association between parkinsonism and a pathogenic variant in the KMT5B gene, expanding the clinical spectrum of KMT5B-related disorders. Background: Neuropsychiatric…Parkinsonism Due to Delayed Neurotoxicity of CAR-T Therapy
Objective: We report a case of secondary parkinsonism due to delayed neurotoxicity induced by ciltacabtagene autoleucel (cilta-cel) chimeric antigen receptor T-cell therapy (CAR-T) as well…Clinical and Genetic Characteristics of PLA2G6-parkinsonism in Southwest China and a Comprehensive Literature Review
Objective: To comprehensively characterize the clinical, imaging and genetic features of PLA2G6-related parkinsonism. Background: Biallelic PLA2G6 mutations are associated with early-onset autosomal recessive parkinsonism, exhibiting a…
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