MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2025 International Congress

    VPS13C: a Modifier Gene causing Suboptimal Response to Levodopa in Early-Onset Parkinson’s Disease

    L. Malfer, C. Piat, O. Ross, Z. Niu, E. Benarroch, R. Savica (Jacksonville, USA)

    Objective: To describe a retrospective clinical study of four cases carrying heterozygous pathogenic variants in the VPS13C gene with a clinical diagnosis of Early-Onset Parkinson’s…
  • 2025 International Congress

    The Global Parkinson’s Genetics Program: Expanding the Diversity of Neurological Disorder Data: 2025 Update

    GP2. Parkinson'S_genetics_program (Chevy Chase, USA)

    Objective: To broaden the available data for Parkinson's Disease (PD) and related disorders by integrating genetic data from more than 115,000 participants worldwide through genotyping…
  • 2025 International Congress

    CAP-003, a CNS-targeted IV-delivered AAV Gene Therapy Developed for Patients with Parkinson’s Disease associated with GBA1 Mutations

    K. Mcdowell, R. Ressler, M. Flynn, B. Wheeler, L. Grigoryeva, A. Armendariz, H. Acharya, P. Denis, J. Granados, P. Tchourilov, C. Pedeferri, M. Brandabur, S. Tole, N. Goeden, N. Flytzanis (Thousand Oaks, USA)

    Objective: CAP-003 is a next-generation gene therapy candidate, comprising a novel brain-tropic capsid paired with hGBA1 cargo, that was developed for administration as a single…
  • 2025 International Congress

    Deep Brain Stimulation and Lesional Surgery in Parkinson’s Disease: Our Experience in Santa Cruz de la Sierra, Bolivia

    E. Gonzalez Delgado, J. Velasco Fortun (Santa Cruz de la Sierra, Bolivia)

    Objective: To evaluate the outcomes and complications of deep brain stimulation (DBS) and ablative surgery in patients with Parkinson’s disease (PD) in our center. Background:…
  • 2025 International Congress

    Local field potential vs image guided programming: clinical trial for optimization the deep brain stimulation in Parkinson’s disease

    A. Martínez Reyes, J. Bejarano Hernández, A. Cadena Fernández, C. Lázaro Hernández, F. Valldeoriola Serra, A. Sánchez Gómez (Barcelona, Spain)

    Objective: To determine the most effective and efficient STN-DBS programming method in PD comparing LFP-GP and IGP focusing on motor improvement, quality of life and…
  • 2025 International Congress

    Intraoperative Local Field Potentials and Selection of Deep Brain Stimulation Programming Contacts in Patients with Essential Tremor and Parkinson’s Disease

    K. Au, W. Vasquez, J. Cheng (Kansas City, USA)

    Objective: To report correlations of intraoperative local field potentials (LFPs) with longitudinal selection of optimal deep brain stimulation (DBS) programming contacts in patients with essential…
  • 2025 International Congress

    Effectiveness and Outcomes of Deep Brain Stimulation revision surgery for Parkinson’s Disease

    MG. Choi, SY. Jo, JH. Lee, SJ. Chung (Goyang-si, Republic of Korea)

    Objective: This study investigated the clinical characteristics, therapeutic efficacy and postoperative outcomes of Parkinson’s disease (PD) patients undergoing deep brain stimulation (DBS) revision surgery Background:…
  • 2025 International Congress

    EEG Correlates of Orthostatic Hypotension in Parkinson’s Disease: Novel Biomarkers for Autonomic Failure

    A. Frohlich, J. Riddle, F. Frohlich, D. Rubinow, E. Dayan, M. Sklerov (Chapel Hill, USA)

    Objective: To identify potential EEG biomarkers associated with orthostatic hypotension in Parkinson Disease (PD) and evaluate their relationship with clinical measures of autonomic dysfunction. Background:…
  • 2025 International Congress

    Individuals With a History of Traumatic Brain Injury Have a Higher Prodromal Burden Than Those Without Such a History

    A. Mcnamara, S. Hansch-Maher, I. Baetu, L. Collins-Praino (Adelaide, Australia)

    Objective: To characterise prodromal presentation in neurologically healthy individuals with and without a history of  traumatic brain injury (TBI), compared to those with  clinically diagnosed…
  • 2025 International Congress

    Patients’ Perspective on Screening for Non-Motor Symptoms in Parkinson’s Disease, A QI Project

    C. Flavin, G. Lamotte, P. Moretti (Salt Lake City, USA)

    Objective: To assess deficiencies in patient care for individuals with Parkinson's disease in neurology clinics, with a particular focus on nonmotor symptoms. Background: While motor…
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