2024 International Congress Archives - Page 103 of 181

LRRK2 I1371V Mutation: Unraveling Pathogenic Mechanisms in Dopaminergic Neurons via Membrane Fluidity & Calcium Dysregulation using PD Patient iPSCs

I. Datta, S. Jagtap, V. Holla, N. Kamble, R. Yadav, P. Pal (Bengaluru, India)
LRRK2 in Parkinson’s Disease: A per-domain rare-variant burden study

S. Parlar, K. Senkevich, E. Yu, J. Ruskey, J. Ahmad, F. Asayesh, D. Spiegelman, C. Waters, O. Monchi, Y. Dauvilliers, N. Dupré, L. Greenbaum, S. Hassin-Baer, I. Miliukhina, A. Timofeeva, A. Emelyanov, S. Pchelina, R. Alcalay, E. Fon, Z. Gan-Or (Montreal, Canada)
LRRK2 inhibition by BIIB122/DNL151 in participants with Pathogenic LRRK2 Variants and Parkinson’s disease: Study Design to Evaluate Safety, Pharmacodynamics and Pharmacokinetics

D. Jennings, S. Huntwork-Rodriguez, J. Kluss, S. Ota, S. Dhuria, R. Maciuca, K. Fraser, B. Hersh, Z. Berger, C. Ho, P. Chin (South San Francisco, USA)
LRRK2-Associated Parkinsonism With and Without In Vivo Evidence of Pathologic Alpha-Synuclein: Clinical and Biomarker Characterization

L. Chahine, D. Lafontant, C. Choi, H. Iwaki, M. Brumm, R. Alcalay, K. Nudelman, A. Dagher, K. Merchant, A. Vo, Q. Tao, C. Venuto, K. Kieburtz, K. Poston, S. Bressman, P. Gonzalez Latapi, B. Avants, C. Coffey, D. Jennings, E. Tolosa, A. Siderowf, K. Marek, T. Simuni (Pittsburgh, USA)
Lumbar Punctures in Parkinson’s Research

A. Navangul, H. Matthews, M. Bartlett, H. Groves, S. Stott, A. Noyce (London, United Kingdom)
Lyme disease presenting as a rapidly progressive MSA-C look alike

L. Zünd-Hofer, F. Brugger (Sankt Gallen, Switzerland)
Lysosomal network defects in parkinsonian patients carrying rare variants in lysosomal hydrolytic enzyme genes

J. Hoenicka, A. Pascual, O. de Fàbregues, M. Frias, L. Vela, M. de Lucca, P. García-Ruiz, C. Feliz, M. Marchen, R. Repossi, G. Fernández, M. Roldán, F. Palau (Esplugues de Llobregat, Spain)
Machine Learning Model Comparison for Freezing of Gait Prediction in Advanced Parkinson’s Disease Patients

J. Watts, A. Khojandi, R. Ramdhani (Knoxville, USA)
Machine Learning-Driven Exploration of Epigenetic Patterns in Huntington’s Disease: Understanding Histone Modification Dynamics

R. Fajar, E. Syfaruddin, S. Putri (Sleman, Indonesia)
Magnetic resonance-guided focused ultrasounds (MRgFUS) thalamotomy for disabling tremor secondary to multiple sclerosis.

A. Menéndez, L. Ispierto, M. Tardaguila, J. Muñoz, C. Ramo-Tello, A. González, R. Alvarez, D. Vilas (Badalona, Spain)