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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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2022 International Congress » Neuropharmacology

Meeting: 2022 International Congress

A dose-response study of the effect of the mGlu2/3 orthosteric antagonist LY-341,495 on the anti-dyskinetic and anti-psychotic effect of the mGlu2 positive allosteric modulator LY-487,379 in the MPTP-lesioned marmoset

S. Nuara, J. Gourdon, P. Huot (Montreal, Canada)

Administration of the mGlu2 positive allosteric modulator BINA as monotherapy improves parkinsonism in the MPTP-lesioned marmoset

C. Kwan, A. Hamadjida, I. Frouni, S. Nuara, J. Gourdon, P. Huot (Montreal, Canada)

Bitopertin, a GlyT1 inhibitor, attenuates the development of dyskinesia in the 6-OHDA-lesioned rat

I. Frouni, W. Kang, D. Bédard, S. Belliveau, C. Kwan, A. Hamadjida, P. Huot (Montreal, Canada)

Chronic administration of bitopertin, a GlyT1 inhibitor, in the dyskinetic 6-OHDA-lesioned rat model of Parkinson’s disease

I. Frouni, W. Kang, D. Bédard, L. Desbiens, C. Kwan, A. Hamadjida, P. Huot (Montreal, Canada)

DaxibotulinumtoxinA for Injection in Adults With Upper Limb Spasticity After Stroke or Traumatic Brain Injury: A Randomized Placebo-Controlled Study (JUNIPER)

A. Patel, M. Munin, Z. Ayyoub, G. Francisco, T. Gross, R. Rubio, J. Kesslak (Lee's Summit, USA)

Effect of the mGlu2/3 orthosteric agonist LY-404,039 on dyskinesia, psychosis-like behaviours, and parkinsonism in the MPTP-lesioned marmoset

W. Kang, S. Nuara, J. Gourdon, P. Huot (Montreal, Canada)

Evaluation of the effect of adding a mGlu2/3 orthosteric antagonist to a highly selective 5-HT2A antagonist on dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset

S. Nuara, J. Gourdon, P. Huot (Montreal, Canada)

Melatonin attenuates the bidirectional Gut-Brain axis mediated inflammation caused by Ambient Particulate Matter (PM2.5) and averts neurodegeneration

SAM. Panda, VGM. Naidu (Guwahati, India)

Neuroprotective effect of Boswellia dalzielii extracts in 6-hydroxydopamine-lesioned rat model of Parkinson’s disease

GL. Ndji Otto, H. Adjia, JP. Mingoas Kilekoung (Bertoua, Cameroon)

Neuroprotective effects of estradiol and progesterone in brain of different age groups of naturally menopausal rats.: A therapeutic potential drug for Parkinson’s disease

P. Kumar, N. Baquer (New Delhi, India)

Protective effects of Hibiscus sabdariffa extracts in 6-hydroxydopamine-lesioned parkinsonism.

A. Hamadjida, G. Ndji Otto, MK. Mingoas Kilekoung (bertoua, Cameroon)

The mGlu2 positive allosteric modulator BINA extends enhances low dose L-DOPA anti-parkinsonian action in the MPTP-lesioned marmoset

C. Kwan, I. Frouni, S. Nuara, J. Gourdon, P. Huot (Montreal, Canada)

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