The prevalence of Parkinson’s disease in a predominantly rural area of North West England
Objective: To calculate the crude and age adjusted prevalence of Parkinson’s disease (PD) in North Cumbria. Background: Prevalence data give insight into disease cause and…Gemini digital twins identified neuro-common and disease-specific drivers of rate of change in NfL in Huntington’s disease, Parkinson disease and Alzheimer disease
Objective: Identify common and disease specific molecular drivers of rate of change in Neurofilament light (NfL) in Huntington’s disease (HD), Parkinson disease (PD) and Alzheimer…Identification of pre-frailty in the elderly through serum metabolomics and its impact on Parkinson’s disease phenotype
Objective: We attempted to better characterize pre-frailty using serum metabolomics in a large cohort of elderly subjects without neurodegenerative diseases. Next, we sought to investigate…Epigenetic clocks suggest accelerated ageing in isolated REM Sleep Behavior Disorder patients
Objective: To investigate biological aging in videopolysomnography (vPSG)-confirmed isolated REM Sleep Behavior Disorder (iRBD) patients and vPSG-negative controls, using DNA methylation-based epigenetic clocks. Background: Isolated…Caregiver burden in Parkinson disease: an updated scoping review
Objective: We performed a scoping review to describe caregiver burden in Parkinson disease (PD) and build on the evidence provided by Mosely at al. [1]…Detection of Camptocormia Using Ultrasound in Parkinson’s Disease
Objective: To investigate whether changes in the lumbar paravertebral muscles (LPM) can be detected using muscle ultrasonography (USG) in patients with Parkinson’s disease (PD, PwP)…Associations between non-motor symptoms and patient characteristics in Parkinson’s disease: A multicenter cross-sectional study
Objective: We aimed to investigate factors associated with non-motor symptoms (NMS) in Parkinson's disease (PD). Background: PD is characterized by a variety of NMS, such…Genetic correlation and potential causal relationship between inflammatory bowel disease and Parkinson’s disease
Objective: The present study investigates shared genetic etiology between inflammatory bowel disease (IBD) and Parkinson’s disease (PD) using correlation and causality-based approaches. Background: The role…Feasibility of in-person and remote delivery of Alexander technique course for care partners of people with neurodegenerative disease
Objective: Test feasibility of in-person and remote delivery via Zoom of Alexander technique (AT) course to improve quality of life for care partners (CP) of…Synaptic density in cortical and subcortical gray matter is associated with mild parkinsonian signs (MPS) in healthy older adults: a [11C] UCB-J PET study
Objective: to investigate if a reduction in cortical and subcortical synaptic density measured in vivo with the synaptic vesicle protein 2A (SV2A) binding [11C] UCB-J…
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