Serum uric acid level as a biomarker in sporadic and familial (p.A53T alpha synuclein carriers) Parkinson’s disease: Longitudinal data from the PPMI study
Objective: To determine whether there are longitudinal differences in serum uric acid level among sporadic Parkinson’s disease (PD) patients, PD patients harboring the p.A53T mutation…Analysis of brain-derived blood exosomes for diagnostics of synucleinopathies
Objective: Here, we aimed to determine if measuring of α-synuclein concentration in these vesicles from oligodendrocytes and neurons can distinguish between patients with MSA or…Identification and Characterization of Selective and High Affinity Small Molecules as Positron Emission Tomography (PET) Imaging Tracers for Pathological Alpha-Synuclein
Objective: The aim is to develop small molecular weight compounds which bind selectively and with high affinity to alpha-synuclein (a-syn) aggregates as diagnostic PET imaging…Methylation status of SNCA gene in patients with Parkinson disease in Russian population
Objective: To study methylation status of SNCA gene in patients with Parkinson disease in Russian population Background: The genetic background of Parkinson disease (PD) has…Automated Immunohistochemical Detection of Skin Depositions of Pathological alpha-Synuclein in Idiopathic REM Sleep Behavior Disorder and Parkinsonism
Objective: The goal of this study was to employ a novel highly sensitive dual-stain immunohistochemical (IHC) assay in the assessment of cutaneous pathological alpha-synuclein (aSyn)…CXCL12 is involved in α-synuclein-triggered neuroinflammation of Parkinson’s disease
Objective: Activated microglia and increased cytokine levels could precede neurodegeneration in neuro-inflammation in A53T mice, and CXCL12 was found increased in plasma CNS-derived exosomes, which…New Neuropathological Staging System for Lewy Body Disease
Objective: Present the validation of the new proposed novel staging system (NSS) for Lewy body disease and compare it against the previously proposed staging systems. Background:…Fine-mapping of SNCA variants in REM sleep behavior disorder identifies distinct associations
Objective: a). Identify variants in the SNCA locus which affect risk for REM Sleep Behavior Disorder (RBD). b). Test variant effects on rate and type…Digital biomarker sensor feature data reflect quality of life judgements (PDQ39) in recently diagnosed Parkinson’s disease patients
Objective: To evaluate the extent to which data derived from smartphone-based testing and passive monitoring are related to what recently diagnosed Parkinson’s disease (PD) patients…Tau and amyloid-beta inclusions are present in pancreatic beta-cells of patients with synucleinopathies
Objective: We have assessed whether tau and amyloid beta deposits might be present in pancreatic tissue of subjects with Parkinson’s and Lewy Body dementia. Background:…
- « Previous Page
- 1
- …
- 52
- 53
- 54
- 55
- 56
- …
- 70
- Next Page »