Altered cerebello-thalamo-cortical pathway in Huntington’s disease
Objective: This study aims to assess the functional integrity of the cerebello-thalamo-cortical (CTC) pathway in patients with Huntington's disease (HD) through transcranial magnetic stimulation (TMS).…Correlation among DNA methylation status and LINE-1 expression in rat brain
Objective: Our objectives were to study the transcriptional expression of L1Rn elements in different brain regions and correlate with corresponding DNA methylation levels. Methods: Real…Assessment of subclinical cerebellar involvement in progressive supranuclear palsy using SUIT based volumetric analysis
Objective: To explore the pattern of cerebellar atrophy if any, in patients with Progressive Supranuclear Palsy (PSP) using the SUIT (Spatially Unbiased atlas template for…Same cerebellar atrophy pattern in hyper- and hypokinetic movement disorders due to mitochondrial cytopathy
Objective: To describe the prevalence and phenotype of movement disorders (MDs) in patients with mitochondrial cytopathy (MC) and corresponding pattern of cerebral atrophy. Background: MCs…Emotional modulation of the startle reflex in essential tremor: Evidence of altered cerebellar input into limbic circuitry?
Objective: To examine whether Essential Tremor (ET) is associated with subtle changes in emotion processing, in parallel with those observed in the cognitive domain, using…Cerebellar atrophy in Parkinson’s disease and its implication for network connectivity
Objective: To determine the effect of cerebellar atrophy on resting-state network abnormalities in individuals with Parkinson's disease. Background: In Parkinson's disease, the cerebellum is a…Density of metabotropic glutamate receptors subtype 1 in de novo patients with Parkinson’s disease using 11C-ITMM PET
Objective: To investigate the mapping of metabotropic glutamate receptor subtype 1 (mGluR1) in elderly normal and de novo patients with Parkinson's disease (PD) using N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-4-11C…An open label trial to test the modulation of cerebellar motor pathways in primary orthostatic tremor using rTMS and fMRI
Objective: In patients with primary orthostatic tremor (OT), we assessed how functional impairment, electrophysiological measures of tremor and long-range connection between the cerebellum and the…Impaired cerebellum to motor cortex associative plasticity in Parkinson’s disease
Objective: To compare the corticocortical paired associative stimulation (PAS)-induced spike-timing dependent plasticity (STDP)-like plasticity between Parkinson's disease (PD) and healthy elder subjects. Background: Patients with…
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