Late onset chorea secondary to antiphospholipid syndrome with radiological correlation on brain FDG-PET: a case report.
Objective: To describe chorea as the initial manifestation of antiphospholipid syndrome (APS) and its radiological correlation on brain FDG-PET as an autoimmune movement disorder. Background:…Patient and Caregiver Perspectives on Patient Burden of Huntington Disease Chorea and the Real‑World Impact of Deutetrabenazine Treatment
Objective: To evaluate self- and caregiver-reported patient burden of Huntington disease (HD) chorea and the impact of deutetrabenazine (DTBZ) treatment on symptom management, quality of…Real-World Evaluation of Deutetrabenazine for Huntington Disease–Associated Chorea in South Korea: Study Design and Baseline Characteristics
Objective: To describe the design and baseline characteristics of a real-world study evaluating the safety and effectiveness of deutetrabenazine (DTBZ) in South Korean patients with…MT200605 for Huntington’s Disease: Nonclinical finding and Phase I Clinical Result
Objective: To summarize the efficacy of the oral MT200605 formulation in a Huntington’s disease (HD) mouse model and current clinical progress of MT200605. Background: MT200605…Efficacy of Rapid-Succession “Flash Song” Music Therapy on Cognitive and Behavioral Symptoms in Outpatients with Juvenile Huntington’s Disease
Objective: To evaluate the clinical feasibility and efficacy of a novel, rapid-succession music therapy intervention ("Flash Song Therapy") on cognitive function, behavioral symptoms, and quality…PPAR-γ-dependent Neuroprotection by Ferulic acid improves Motor deficits in 3-nitropropionic acid model of Huntington’s disease in rats
Objective: This study investigates the neuroprotective role of FA in 3-nitropropionic acid (3-NP) model of HD through PPAR-γ–mediated mechanisms. Background: Huntington disease (HD) is a…Effectiveness and Safety of Deutetrabenazine in Chinese Patients with Huntington’s Disease-associated Chorea: A Multicenter Phase 4 Study
Objective: To evaluate the effectiveness and safety of deutetrabenazine (DTBZ) in Chinese patients with Huntington’s Disease (HD)-associated chorea. Background: Chorea is a key symptom of…Perception of Early-Intervention Therapies and Clinically Meaningful Delays in Huntington’s Disease Onset and Progression: The Pre-HDBOI Study
Objective: To characterize willingness among people with premanifest Huntington’s disease (PwPHD) to consider early-intervention therapies if available, the minimally acceptable delay in HD onset/progression, and…Antidepressants in Huntington’s Disease: A Meta Analysis of Mood and Motor Outcomes with Placebo-controlled Trials
Objective: To evaluate the efficacy of antidepressants for depression in Huntington’s disease (HD). Background: Depression is highly prevalent in HD. Despite frequent clinical use of…Efficacy and Adverse Events of Tetrabenazine, Deutetrabenazine, and Valbenazine in Huntington’s Disease
Objective: To compare the efficacy and safety of tetrabenazine, deutetrabenazine, and valbenazine for chorea and neuropsychiatric outcomes in Huntington’s disease (HD). Background: Vesicular monoamine transporter…
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