Efficacy of Novel A2A/A1 Antagonist in Motor and non-Motor Symptoms of MPTP-Treated Macaques
Objective: Our primary objective was to test the novel adenosine A2A/A1 receptor antagonist IDAA-338 in alleviating Parkinsonian symptoms when given as a mono or as…Cognitive Outcome in Pantothenate Kinase-Associated Neurodegeneration (PKAN) Treated with Deep Brain Stimulation (DBS):Case Report
Objective: To assess cognitive outcome in PKAN treated with DBS Background: PKAN is a rare neurodegenerative disorder with pediatric onset & dystonic features. Motor symptoms…Adult-onset Niemann-Pick C in India: phenotype and genotype
Objective: This study was aimed to describe the clinical, radiological, and molecular profile of adults affected by NPC. Background: Adult-onset Niemann-Pick C (NPC) is a…Exploring the Prevalence of Subjective Cognitive Decline and Mild Cognitive Impairment in Participants of the Luxembourg Healthy Ageing Study
Objective: Determine prevalence of Subjective Cognitive Decline(SCD) and Mild Cognitive Impairment(MCI) in participants of the Luxembourg Healthy Ageing(HeBA) Study. Background: Cognitive impairment can present as…The East London Parkinson Disease Project: updated results from engaging a diverse population in research
Objective: The East London Parkinson Disease (ELPD) project is a platform study aiming to understand the manifestations and determinants of Parkinson’s disease in a diverse…Characterisation and longitudinal significance of subjective cognitive decline in GBA and LRRK2 Parkinson’s disease
Objective: To investigate the clinical characteristics and predictive value associated with subjective cognitive decline (SCD) in people with Parkinson’s disease (PD) carrying pathogenic GBA or…Exploring the Root of Cognitive Decline in People Living with Parkinson’s Disease: An Analysis of MoCA Scores, Neuropsychiatric Symptoms, and Patient-Reported Outcomes
Objective: To evaluate cognitive decline in people living with PD (PwP), to determine to which degree different neuropsychiatric symptoms are risk factors for cognitive decline…Attitudes and Beliefs Towards Medication Burden and Deprescribing in Parkinson Disease
Objective: To examine the attitudes and beliefs about medication burden and deprescribing among persons living with Parkinson disease (PD) Background: Deprescribing of potentially inappropriate medications…Deep brain stimulation of bilateral ventral intermediate nucleus in patients with neuronal intranuclear inclusion disease
Objective: To evaluate the effect and the side effects of deep brain stimulation on the tremor of a patient with neuronal intranuclear inclusion disease (NIID).…Can gait instability indicate the cognitive function of people with Parkinson’s disease?
Objective: This study aimed to analyze the association between cognition and various speed-based gait instability in people with Parkinson’s disease. Background: Automatic movement and coordination…
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