Perspective of people living with early Parkinson’s Disease: most common, burdensome, and worrisome symptoms
Objective: To assess the most common, burdensome and worrisome symptoms experienced by people living with early Parkinson’s Disease (ePD). Background: Research on symptom frequency and…The effects of DL-3-n-butylphthalide in patients with mild cognitive impairment due to Parkinson’s disease: A multicenter, randomized, double-blind, placebo-controlled trial
Objective: To assess the therapeutic effect of DL-3-n-butylphthalide on cognitive impairment associated with Parkinson’s disease (PD). Background: PD associated cognitive impairment are attracting attention because…Alterations in neural processes of cognitive control in asymptomatic heterozygous mutation carriers in the Parkin gene
Objective: Investigating heterozygous Parkin gene (PRKN) mutation carriers to evaluate the potential association of this mutation with an alteration of cognitive control processes. Background: Recessively…Disease Progression in Patients with PLA2G6-related Parkinsonism: A Longitudinal Study
Objective: To investigate disease progression of PLA2G6-related parkinsonism in a longitudinal study. Background: There is a paucity of follow-up studies on disease progression in PLA2G6-related…The course of cognitive impairment in Parkinson’s disease patients with Сovid-19
Objective: A comparative analysis of the characteristics of cognitive impairment in Parkinson's disease patients with and without Сovid-19. Background: Covid-19 infection strongly affects the central…Evaluating Cognitive Status in Parkinson’s Disease Using a Software-based Eye-Tracking Platform: Preliminary Results of the PALOMA Clinical Trial
Objective: To investigate the correlation between the cognitive status of Parkinson's disease (PD) patients and oculomotor parameters captured by a software-based eye-tracking platform using artificial…Cleaved plasma kininogen is associated with unfavorable cognitive outcome in Parkinson’s disease
Objective: The aim of this study was to examine the association between kininogen cleavage in plasma and cognitive outcome in Parkinson’s disease (PD). Background: No…Uncovering Non-Motor Subtypes in Parkinson’s Disease through Machine Learning
Objective: This study aims to uncover subtypes of Parkinson’s disease (PD) through unsupervised machine learning (ML), based on the predicted evolution of non-motor symptoms (NMS).…Efficacy of Novel A2A/A1 Antagonist in Motor and non-Motor Symptoms of MPTP-Treated Macaques
Objective: Our primary objective was to test the novel adenosine A2A/A1 receptor antagonist IDAA-338 in alleviating Parkinsonian symptoms when given as a mono or as…Cognitive Outcome in Pantothenate Kinase-Associated Neurodegeneration (PKAN) Treated with Deep Brain Stimulation (DBS):Case Report
Objective: To assess cognitive outcome in PKAN treated with DBS Background: PKAN is a rare neurodegenerative disorder with pediatric onset & dystonic features. Motor symptoms…
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