Frequency dependent interindividual variability of the deep brain stimulation effect on upper-limb bradykinesia
Objective: To demonstrate that there are interindividual differences in the response of upper limb bradykinesia to subthalamic deep brain stimulation (STN-DBS) in patients with Parkinson’s…Deep Brain Stimulation in Generalized Dystonia Caused by PRKRA Mutation
Objective: Dystonia is a hyperkinetic movement disorder with a complex pathophysiology. The medical treatment includes pharmacological treatment, including botulinum toxin (BoNT), which is considered the…Digital Biomarkers for Deep Brain Stimulation Programming in PD
Objective: This study investigates changes in EEG activity of Parkinson's disease (PD) patients with subthalamic nucleus (STN) deep brain stimulation (DBS) to identify neural biomarkers…Acute Stimulation-Induced Ataxia From Thalamic Deep Brain Stimulation
Objective: To characterize stimulation-induced ataxia in Essential Tremor patients treated with VIM DBS. Background: In Essential tremor (ET) patients with medically refractory tremor, deep brain…Analysis of bilateral subthalamic nucleus deep brain stimulation in patients with monogenic forms of Parkinson’s disease: PRKN and LRRK2
Objective: The aim of this study is to compare the clinical and pharmacological response of bilateral STN DBS in patients with monogenic forms of PD…Changes in anticholinergic burden in patients with Parkinson’s disease (PD) after bilateral deep brain stimulation (DBS) of the globus pallidus (GP) and subthalamic nucleus (STN)
Objective: To evaluate the effect of GP and STN DBS upon anticholinergic medication burden in patients with PD. Background: Medications with anticholinergic effects are commonly…Non-motor fluctuations in People with Parkinson’s considering Deep Brain Stimulation surgery
Objective: In this study we examine non-motor symptom (NMS) fluctuations reported by People with Parkinson’s (PWP) pursuing Deep Brain Stimulation (DBS) surgery using the MDS…Pallidal firing rate and alpha oscillations correlate with the severity of clinical symptoms in patients with dystonia
Objective: To examined how pallidal activity correlates with symptom severity across dystonic patients. Background: The internal segment of globus pallidus (GPi) is the most common…Video-guided Optimization of Stimulation Settings in Patients with Parkinson’s Disease and Deep Brain Stimulation
Objective: To investigate whether video-based evaluations of motor control and changes of predefined stimulation parameters via patient programmer can improve motor status in Parkinson’s disease…PHENOTYPIC DESCRIPTION OF TWO UNREPORTED FAMILIES WITH ANO3 DYSTONIA
Objective: This is the phenotypic description of two families affected by hereditary dystonia associated to gene ANO3 mutation (DYT24), one with a heterozygous verisimilarly pathogenic…
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