Has patients affected by REM sleep Behavior Disorder a specific brain glucose metabolism pattern?
Objective: This study aimed at evaluating brain glucose metabolism in patients affected by REM sleep behavior disorders (RBD) compared to Parkinson’s Disease (PD), Lewy Body…The impact of APOε4 polymorphisms and mutations in the GBA gene on the clinical features of Dementia with Lewy Bodies among Ashkenazi Jews
Objective: We aimed to explore the frequency and clinical impact of APOε4 polymorphisms in a cohort of Ashkenazi Jewish (AJ) patients with Dementia with Lewy…Zonisamide improves parkinsonism in DLB patients: A randomized phase 3 trial
Objective: To verify the efficacy and safety of zonisamide (ZNS) for parkinsonism in patients with dementia with Lewy bodies (DLB). Background: DLB parkinsonism is responsive…Expanding the NINDS Parkinson’s Disease Biomarkers Program – Utilizing a Major Biomarker Resource to Address Atypical Parkinsonisms and Related Conditions
Objective: Expansion of a carefully curated resource for clinical and biosample data to address a critical need for biomarker discovery in Atypical Parkinsonisms and related…Effects of zonisamide, an anti-parkinsonian drug, on cognition and BPSD in DLB patients: A post-hoc analysis of DLB Ph2 study
Objective: Based on the results of a phase 2 study to evaluate the efficacy of zonisamide in improving parkinsonism accompanying dementia with Lewy Bodies (DLB),…[11C]PK11195 PET Imaging Reveals Neuroinflammation in Dementia with Lewy Bodies: NIMROD Study
Objective: To determine if subjects with dementia with Lewy bodies(DLB) have increased microglial activation in vivo compared to matched healthy controls as assessed using PET…Impaired Color Vision in Patients with DLB or Prodromal DLB.
Objective: We sought to characterize the prevalence of color vision impairment in DLB patients and investigate how color vision impairment in DLB patients was associated with other…White matter lesions and peripheral vessel reactivity in dementia with Lewy bodies
Objective: We aimed to assess the significance of white matter hyperintensities (WMHs) in dementia with Lewy bodies (DLB) and their contribution to phenotype of the…Improved diagnosis of dementia with Lewy bodies by the combination of Tc-99m ECD SPECT with eZIS analysis and quantitative TRODAT-1 SPECT images
Objective: The development of easily useful neuroimaging may resolve to the delays of diagnosis. Background: Dementia with Lewy bodies (DLB) is easy to be misdiagnosed…Voxel-based Analysis of Cholinesterase Inhibitor Response in Lewy Body Disorders: A Prospective Observational Study
Objective: The objective is to investigate functional neuroimaging correlates of response to ChEIs in LBD. Background: Lewy body disorders (LBD), including dementia with Lewy bodies…
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