Are people with Parkinson’s disease living in care homes in the UK underserved? Identifying models of care and barriers to care access
Objective: To conduct a nationwide online survey of Parkinson's disease nurse specialists (PDNS) and Parkinson's UK information staff to gain insight into current models of…sFIDA: A sensitive diagnostic assay for quantification of α-synuclein aggregates
Objective: Optimizing of our sFIDA (surface-based fluorescence intensity distribution analysis) assay for specific detection and quantification of single α-synuclein aggregates. Background: Parkinson's disease (PD) is…Deficiency of HGprt in Lesch-Nyhan disease is associated with abnormal dopaminergic neurodevelopment in vivo
Objective: To determine the in vivo effects of hypoxanthine-guanine phosphoribosyl transferase (HGprt) deficiency on dopaminergic neurodevelopment in a genetic mouse model of Lesch-Nyhan disease (LND).…Chronic cerebral hypoperfusion accelerates cognitive dysfunction and microvascular impairment in the MPTP mouse model of Parkinson’s disease
Objective: To evaluate cerebral hypoperfusion on cognitive dysfunction and related microvascular impairment in the MPTP mouse model. Background: Vascular pathology and Parkinson's disease (PD) pathology…European pediatric normative values for the scale for assessment and rating of ataxia (SARA)
Objective: To obtain international age-related normative values for the SARA in healthy European children. Background: The Scale for Assessment and Rating of Ataxia (SARA) is…Developmental movement patterns resemble movement disorder features in healthy babies and toddlers
Objective: In healthy children (0-3 years), we investigated the association between developmental motor patterns and movement disorder features. Background: The developing nervous system produces a…
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