Ginsenoside Rb1 protects dopaminergic neurons through Foxm1-Nurr1 pathway in mice model of Parkinson’s disease
Objective: In the present work, we investigated the protective effects of ginsenoside Rb1 in dopaminergic neurons through Foxm1-Nurr1 pathway in mice model of Parkinson’s disease.…Chlorogenic acid exerts anti-neuroinflammatory effect by suppressing NF-κB pathway in Parkinsonian mice model
Objective: The objective of this study was to investigate the anti-neuroinflammatory effect of chlorogenic acid (CGA) in the 1-methyl-4-phenyl-1,2, 3, 6- tetrahydropyridine (MPTP) model of…Yerba Mate (Ilex paraguaiensis) protects dopaminergic neurons degeneration and improve their maturation in culture
Objective: To evaluate the effect of Mate leaves extracts on the survival and maturation of dopaminergic neurons in vitro. Background: Parkinson's disease (PD) is caused…Primary familial brain calcification – The impact of calcifications on the development of motor symptoms
Objective: The aim of the present study was to investigate whether the nigro-striatal system in a genetic mouse model of primary familial brain calcification (PFBC)…Controlled neural organoids grafting promotes functional recovery in experimental parkinsonism
Objective: We propose that the striatal transplantation of 3D-neural organoids of controlled cell size and cell content, named "Controlled Neural Organoids" (CNOs), could circumvent the…Vitamin B3 and Neurodevelopment in Parkinson’s Disease
Objective: This study aimed to investigate the potential of vitamin B3 to promote the conversion of stem cells to mature central nervous system (CNS) neurons.…Dopaminergic stem cells reside in the rostral migratory stream
Objective: To analyze if the adult rostral migratory stream (RMS) harbors neural stem cells with the potential to create dopaminergic neurons for the olfactory bulb…A53T mutant human α-synuclein BAC transgenic mice as a model for Parkinson’s disease
Objective: The aim of this study is to create mouse models reproducing the course of PD pathology and symptoms. Background: Parkinson's disease (PD) is a…Possible neurotoxic hazards of common adulterants in Tea among Drosophila; ascertainment of toxicity of Tea preparations from local shops of an Indian city
Objective: The present study assesses the neurotoxic implications of common adulterants of Tea in drosophila system in terms of tremor behaviour and neurochemical changes. Also…Adult neurogenesis is impaired in pink1-/- zebrafish (Danio rerio)
Objective: To determine whether PINK1 deficiency impairs adult neurogenesis in a tractable vertebrate model of PINK1-related Parkinson's disease (PD). Background: PD is characterized by loss…
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