Remotely acquired speech-based biomarkers and their relation to motor and cognitive functions in Parkinson’s disease
Objective: To evaluate the feasibility and clinical validity of remote, digital speech-based cognitive and speech motor assessments in Parkinson’s disease (PD). Background: Speech in PD…Tongue Fasciculations in Amyotrophic Lateral Sclerosis Compared Between Electromyography and Transoral Ultrasonography
Objective: To compare the detection of tongue fasciculations between electromyography (EMG) and transoral motion-mode ultrasonography (TOMU) in patients with amyotrophic lateral sclerosis (ALS), and to…A case of difficulty extubating after General Anesthesia Deep Brain Stimulation (DBS) surgery
Objective: Dysfunction in speech, respiration, and swallowing can severely compromise the well-being of Parkinson’s disease (PD) patients. Here, we present a rare case of acute…Ante-Mortem Motor Speech Profiles in Postmortem Confirmed Atypical Parkinsonisms
Objective: Differences in motor speech profiles may aid in diagnosis of atypical parkinsonisms. This is a retrospective study that characterizes ante-mortem motor speech profiles in postmortem…Network determinants of stimulation-induced speech impairment after subthalamic DBS in Parkinson’s disease
Objective: To delineate hemisphere-specific, local, and network-level mechanisms underlying stimulation-induced speech impairment after subthalamic deep brain stimulation (STN-DBS). Background: STN-DBS can improve but also worsen…Progressive Lifelong Chorea with Spastic Paraparese and Cerebellar Ataxia Associated with Two Heterozygous Variants in the SYNE1 Gene: A Case Report
Objective: To report a case harboring two different heterozygousSYNE1 variants whose combined effect is suspected tounderlie a complex neurogenetic phenotype Background: SYNE1 encodes nesprin-1, one…Speech and Voice Changes after Intensive Therapy in Parkinson’s Disease
Objective: To examine the effects of a modified intensive speech therapy program on perceptual and objective acoustic measures in Hebrew-speaking individuals with Parkinson’s disease (PD).…Baseline auditory-perceptual speech ratings predict improvement in voice intensity after group-based speech intervention in Parkinson’s disease
Objective: To explore baseline predictors of improvement in voice intensity following group-based speech intervention in PD. Background: Speech and voice impairments are common in PD…Improving Automatic Speech Recognition for Speakers with Parkinson’s disease
Objective: 1. Obtain high-fidelity, speech data from 400 people with Parkinson’s (PWP) to train automatic speech recognition (ASR) systems.2. Develop and implement procedures to recruit,…Effectiveness of Intensive Speech Treatment for Friedreich’s Ataxia
Objective: 1. Test feasibility of providing online intensive speech treatment to people with Friedreich’s Ataxia (FA)2. Compare benefits of two treatment targets (vocal loudness-LSVT LOUD;…
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