Quantitative Neurodegenerative Risk Modelling and Clinical Score Prediction Using Mixed Reality
Objective: This study investigates the potential of mixed reality (MR) tool for multimodal data collection from individuals with Parkinson’s disease and examines the use of…Identifying Informative Speech Tasks for Detecting Clinically Relevant Changes in Parkinson’s Disease
Objective: To identify the most informative speech tasks for detecting clinically relevant speech changes in Parkinson’s Disease (PD) and to develop a streamlined, data-driven assessment…Remotely acquired speech-based biomarkers and their relation to motor and cognitive functions in Parkinson’s disease
Objective: To evaluate the feasibility and clinical validity of remote, digital speech-based cognitive and speech motor assessments in Parkinson’s disease (PD). Background: Speech in PD…Tongue Fasciculations in Amyotrophic Lateral Sclerosis Compared Between Electromyography and Transoral Ultrasonography
Objective: To compare the detection of tongue fasciculations between electromyography (EMG) and transoral motion-mode ultrasonography (TOMU) in patients with amyotrophic lateral sclerosis (ALS), and to…A case of difficulty extubating after General Anesthesia Deep Brain Stimulation (DBS) surgery
Objective: Dysfunction in speech, respiration, and swallowing can severely compromise the well-being of Parkinson’s disease (PD) patients. Here, we present a rare case of acute…Ante-Mortem Motor Speech Profiles in Postmortem Confirmed Atypical Parkinsonisms
Objective: Differences in motor speech profiles may aid in diagnosis of atypical parkinsonisms. This is a retrospective study that characterizes ante-mortem motor speech profiles in postmortem…Network determinants of stimulation-induced speech impairment after subthalamic DBS in Parkinson’s disease
Objective: To delineate hemisphere-specific, local, and network-level mechanisms underlying stimulation-induced speech impairment after subthalamic deep brain stimulation (STN-DBS). Background: STN-DBS can improve but also worsen…Progressive Lifelong Chorea with Spastic Paraparese and Cerebellar Ataxia Associated with Two Heterozygous Variants in the SYNE1 Gene: A Case Report
Objective: To report a case harboring two different heterozygousSYNE1 variants whose combined effect is suspected tounderlie a complex neurogenetic phenotype Background: SYNE1 encodes nesprin-1, one…Speech and Voice Changes after Intensive Therapy in Parkinson’s Disease
Objective: To examine the effects of a modified intensive speech therapy program on perceptual and objective acoustic measures in Hebrew-speaking individuals with Parkinson’s disease (PD).…Baseline auditory-perceptual speech ratings predict improvement in voice intensity after group-based speech intervention in Parkinson’s disease
Objective: To explore baseline predictors of improvement in voice intensity following group-based speech intervention in PD. Background: Speech and voice impairments are common in PD…
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