Zonisamide ameliorates levodopa-induced dyskinesia via striatal cholinergic system in a rat model of Parkinson’s disease
Objective: To investigate the difference in results according to the mode of levodopa administration and the effect of zonisamide (ZNS) on striatal cholinergic system, we…Toning down SPNs to improve motor responses to dopaminergic stimulation in Parkinson’s disease
Objective: This study was aimed at examining whether decreasing the baseline SPN firing frequency towards the low activity found in normal conditions reduces LID. Background:…Crack Dancing: An Uncommon Drug-Induced Chorea
Objective: To report a unique case of cocaine induced choreiform dyskinetic movements with literature review of this condition. Background: Various abnormal movements have been known…A phase Ib trial studying the safety and tolerability of IRL790 in patients with Parkinson’s disease and levodopa-induced dyskinesia
Objective: The primary objective was to investigate the safety and tolerability of IRL790 in PD patients with LID in a randomized controlled trial. Background: IRL790…Clinical experiences in Whole systems Ayurveda Management of Parkinson’s Disease
Objective: PD Assessment of Ayurveda management using UPDRS -Motor, Hoehn & Yahr staging, Activity of Daily Living % (ADL). Background: Ayurveda holistic management comprises an…Item Response Theory Analysis of the Unified Dyskinesia Rating Scale Items
Objective: To investigate the measurement characteristics of the Unified Dyskinesia Rating Scale (UDysRS) using item response theory (IRT) approaches. Background: The UDysRS has become the…What is the relationship between dyskinesia and performance of activities of daily living in patients with Parkinson’s disease?
Objective: The aim of this study was to determine which of drug-induced dyskinesia (DID) or other symptoms of Parkinson's disease (PD) had the most impact…Individualization of levodopa treatment using a microtablet dispenser and ambulatory accelerometry
Objective: This four-week open-label observational study describes the effect of introducing a microtablet dose dispenser and adjusting doses based on objective free-living motor symptom monitoring…Chronological view of peak and diphasic dyskinesia, wearing off and freezing in Parkinson’s disease: 1212 Korean population
Objective: To evaluate the gross chronological trend of 4 motor complications - peak dose dyskinesia, diphasic dyskinesia, wearing off and freezing. Background: Dyskinesia, wearing off…Differences in the Unified Dyskinesia Rating Scale based on age, Parkinson´s Disease and Dyskinesias duration
Objective: To analyze the Unified Dyskinesia Rating Scale (UDysRS) scores on Historical, Objective parts and their differences based on age, Parkinson´s disease (PD) and dyskinesias…
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