STN deep brain stimulation can directly suppress levodopa-induced dyskinesia in Parkinson’s disease
Objective: The study aims to evaluate the effect of bilateral STN-DBS on levodopa-induced peak-dose dyskinesia in patients with PD. Background: Dyskinesia is among the most…A novel mGlu4 PAM alleviates motor symptoms in primate models of PD and of LID
Objective: Objective was to assess the therapeutic potential of our novel mGlu4 positive allosteric modulator (PAM), foliglurax, as an anti-parkinsonian treatment in gold-standard primate models.…Toe dystonia in Parkinson’s disease: Impact of subthalamic nucleus deep brain stimulation
Objective: To analyze the prevalence and the evolution of toe dystonia in parkinson's disease (PD) patients candidate to subthalamic nucleus deep brain stimulation (STN-DBS). Background:…What happens when I watch a ballet? Preliminary fMRI findings on somatosensory empathy in Parkinson Disease
Objective: To investigate the neural components of the mirror sensor-motor system recruited by a dance movement in a motor disorder, such as PD is. Background:…Advanced Parkinson’s disease Diagnosis and Treatment Trends in Israel – Sub-Analysis of the OBSERVE-PD Multi-Country, Cross-Sectional Study
Objective: The primary objective of this observational study was to evaluate the proportion of Parkinson’s disease (PD) patients identified as advanced PD (APD) patients according…Determinants of absence of dyskinesia in Parkinson’s disease patients with treatment beyond 10 years
Objective: This study aims to explore the determinants for absence of dyskinesia in patients with Parkinson’s disease (PD) based on a large cohort of Chinese…STN-DBS causing persistent dyskinetic movements in OFF-State
Objective: Transient choreatic movements are known as side effects of DBS of the dorsolateral STN in Parkinson disease (PD). Persistent “brittle” dyskinesia have been reported…Nonlinearities in outcome-specific hazard of motor and nonmotor long-term complications of Parkinson’s disease
Objective: To estimate the specific hazard of motor and nonmotor milestones of Parkinson's disease (PD) progression in the long term. Background: Parkinson’s disease greatly varies…Patients experiencing peak-dose dyskinesia use re-distribution of involuntary movement amplitude throughout their body to minimize the functional impact of dyskinesia
Objective: To investigate the presence of a strategy in dyskinesia amplitude re-distribution enabling patients to perform motor tasks. Background: In Parkinson’s disease (PD), occurrence of…Absence of wearing-off in Parkinson’s disease patients with treatment beyond 10 years
Objective: This study aims to explore the determinants for absence of wearing-off in patients with Parkinson’s disease (PD) based on a large cohort of Chinese…
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