Dyskinesias-reduced-self-awareness and theory of mind in Parkinson’s disease: A novel frame of interpretation
Objective: To analyze the existence of a relationship between Dyskinesias-reduced-self-awareness (DRSA) and abilities related to cognitive and affective Theory of Mind (ToM), which may represent…ADS-5102 (amantadine HCl) extended-release capsules reduced levodopa-induced dyskinesia in the phase 3 EASE LID study
Objective: To investigate the efficacy and safety of ADS-5102 (amantadine HCl) extended release capsules 340 mg daily at bedtime for the treatment of levodopa-induced dyskinesia…Validation of an electronic motor diary for patients with Parkinson’s disease
Objective: To determine the reliability and compliance to electronic motor diary in patients with PD. Background: Complexity of motor complications in Parkinson's disease (PD) makes…Characterization of striatal TH-immunoreactive cells in chronic and acute L-DOPA treatment in a mice model of Parkinson´s disease
Objective: To characterize Tyrosine Hydroxylase immunoreactive cells (TH-ir) in a mouse model of hemiparkinsonism and L-DOPA induced dyskinesia. Background: L-DOPA-induced dyskinesias (LID) are a severe…The relationship between impulse control disorders and dyskinesia in Parkinson´s disease: The ALTHEA study
Objective: To report (1) the relationship between the occurrence of impulse control disorders (ICDs) and dyskinesias, and (2) the correlations between specific ICDs and the…Status of NPF-QII after six years: Updates to the dataset
Objective: To describe the status and recent findings from the National Parkinson Foundation's Quality Improvement Initiative (NPF-QII), an 8,179 subject observational clinical study conducted at…A strategy to classify Parkinson’s disease patients with dyskinesia: The analysis of center of pressure with impact of cognitive loading
Objective: To propose a strategy to classify Parkinson's disease (PD) with/without dyskinesia by analyzing center of pressure (CoP) with impact of cognitive loading. Background: Cognitive…Is levodopa-induced dyskinesia in Parkinson’s disease associated with increased blood brain barrier permeability and volumetric changes?
Objective: The aim of this study was to explore the angiogenetic hypothesis for Levodopa-induced-dyskinesia (LID) using advanced MRI methods in patients with Parkinson's disease (PD).…Symptom progression in a large cohort of Parkinson’s disease cases in a clinical practice setting
Objective: To assess the temporal profile of motor and non-motor symptoms in Parkinson's disease. Background: Parkinson's disease is characterized by varying combinations of motor and…Detailed evaluation of dyskinesias using multiple endpoints in a randomized, placebo-controlled trial of Parkinson’s disease patients with motor fluctuations
Objective: To analyze all dyskinesia data from a Phase 2b trial of fluctuating Parkinson patients in order to understand the overall impact a study drug…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.