Characteristics of Cortical Beta Bursts in Parkinson’s disease
Objective: 1. Do patients with PD experience changes in cortical beta bursts in both the low and high β frequency bands?2. Are bursts of different…Acute administration of methylphenidate modulates functional connectivity during the processing of irrelevant stimuli in Parkinson’s disease patients
Objective: Examine the effects of a single dose of methylphenidate (MPD), on event-related functional connectivity (FC), in patients with Parkinson’s disease (PD). Background: Recent studies…Non-Rapid Eye Movement Sleep Neurophysiological Alterations in Lewy Body Disorders
Objective: To characterise NREM sleep neurophysiology across multiple domains in Lewy body disorders (LBDs) relative to healthy controls. Background: Sleep disturbances are highly prevalent in…Sleep Slow-Wave Activity Topography and Dynamics in PD: Relationships with Resting-State fMRI data and Glymphatic Clearance
Objective: We propose that abnormal EEG power dynamics during sleep are associated not only glymphatic dysfunction but also signal fundamental changes in resting-state functional connectivity…Electroencephalographic and Functional Magnetic Resonance Imaging Analysis of Daytime Sleepiness in Parkinson’s Disease
Objective: To explore the electroencephalographic (EEG) characteristics and brain functional connectivity patterns in Parkinson's disease (PD) patients with daytime sleepiness. Background: Daytime sleepiness is a…Developing non-invasive EEG biomarkers for Parkinson’s disease using concurrent subthalamic nucleus/cortical recording as ground truth.
Objective: In the present study, we aimed to: (1) isolate the motor cortical EEG activity responsible for translating subthalamic nucleus (STN) beta hypersynchrony into bradykinesia;…The Therapeutic Landscape of SSPE: A Systematic Review of Antiviral and Immunomodulatory Modalities
Objective: To systematically map the global therapeutic landscape of SSPE interventions, specifically characterizing drug regimens, dosages, administration routes, and monotherapy versus combination protocols. Background: SSPE…Increased Pre-Alpha EEG Functional Connectivity Forecasts Future Cognitive Decline in Parkinson’s Disease
Objective: To evaluate whether resting-state EEG functional connectivity (rsEEG-FC) forecasts cognitive decline three years later in Parkinson’s disease (PD). Background: Cognitive performance and trajectories of…Burst versus Conventional Deep Brain Stimulation Engage Distinct Cortico-Subthalamic Circuit Dynamics in Parkinson’s Disease
Objective: To characterize the neural effects of burst DBS (bDBS) on cortico-subthalamic circuit dynamics in Parkinson’s disease (PD) and determine whether they differ from conventional…Effects of Targeted Memory Reactivation during Sleep on Motor Memory Consolidation in Parkinson’s Disease
Objective: To study whether targeted memory reactivation (TMR) during sleep improves consolidation of a motor sequence learning task in people with Parkinson’s disease (PD) and…
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