Benefits and Risks of Staged Bilateral versus Unilateral VIM DBS for Essential Tremor
Objective: To compare the benefits and risks of staged bilateral versus unilateral VIM DBS using the largest ET DBS clinical trial dataset available to date.…Cortical and cerebellar excitability in essential tremor
Objective: To investigate the functional state of motor cortex excitability and the involvement of the cerebello-thalamo-cortical pathway using transcranial magnetic stimulation (TMS) in patients with…Using fMRI-based multivariate pattern analysis to differentiate between hyperkinetic movement disorders
Objective: We aimed to investigate differences in functional magnetic resonance imaging (fMRI) brain responses across hyperkinetic movement disorders (HMDs) during a bilateral finger-tapping task.We aimed…Preclinical Characterization of Suvecaltamide for Essential Tremor
Objective: To characterize the in vitro T-type calcium (CaV3) channel target pharmacology and in vivo anti-tremor profile of suvecaltamide (JZP385, CX-8998). Background: CaV3 channels, a…Comparison between clinical and kinematic assessment of bradykinesia
Objective: To compare the clinical and kinematic assessment of bradykinesia (movement slowness). Background: Bradykinesia may be present not only in Parkinson’s disease (PD), but also…Network detection and connectivity analysis to predict DBS-induced ataxia in essential tremor
Objective: We aim to differentiate networks associated with deep brain stimulation (DBS) induced ataxia in essential tremor (ET) patients and test if connectivity to these…Therapies, Research Funding and Racial Diversity in Essential Tremor: A Systematic Review of the Literature
Objective: To analyze controlled clinical trials in essential tremor (ET) spanning the last 50 years in order to identify potential shortcomings in the therapeutic clinical…Diagnosed and Drug-Treated Prevalence of Essential Tremor in Adult Patients: Retrospective Analyses of Two US Healthcare Claims Databases
Objective: Estimate the prevalence of diagnosed and drug-treated essential tremor (ET) in the adult population using 2 US healthcare claims databases. Background: ET is a…Longitudinal study of clinical and neurophysiological features of essential tremor
Objective: This study investigates how motor and non-motor manifestations of essential tremor (ET) progress over time. Background: ET is a common and heterogeneous movement disorder…Clinical effectiveness and economic impact of transcutaneous afferent patterned stimulation therapy for essential tremor in a real-world setting: protocol for a pragmatic trial
Objective: To determine the feasibility of delivery, clinical effectiveness, healthcare resource utilization (HCRU) and costs of transcutaneous afferent patterned stimulation (TAPS) therapy for the treatment…
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