Distinct cholinergic reactivity to dopamine is related with differed parkinsonian tremor responsiveness
Objective: We aimed at exploring the mechanisms of differed tremor responsiveness to dopamine through investigating the cholinergic and dopaminergic reactivity during dopamine administration in PD.…Distinct memory networks in Parkinson’s disease (PD) and Alzheimer’s disease (AD): Effects of APOE
Objective: As part of the Ontario Neurodegenerative Disease Research Initiative, we investigated group differences in functional connectivity within two distinct memory networks: posterior medial network…Deficient interhemispheric connectivity underlies movement irregularities in Parkinson’s disease
Objective: The aim of this study was to investigate whether impaired execution of drawing spirals relates to deteriorations in interregional connectivity. Background: Movement execution is…DO FREEZING OF GAIT AND GAIT AUTOMATICITY IN PARKINSON’S DISEASE SHARE THE SIMILAR NEURAL SUBSTRATE?
Objective: To verify if freezing of gait (FOG) in Parkinson’s disease (PD) and gait automaticity share a similar neural substrate. Background: FOG in PD may…Tremor in dystonia is associated with increased brain activity in the cerebellum and pallidum
Objective: To identify brain regions showing tremor-related activity in patients with dystonic tremor syndrome. Background: Dystonic tremor syndromes are highly burdensome and treatment is often…Inter-network connectivity dynamics underlie compensatory mechanisms in prodromal Parkinson’s disease
Objective: We aimed to investigate the dynamics of inter-network connectivity among non-manifesting GBA and LRRK2 mutation carriers. Background: The prodromal phase of Parkinson’s disease (PD)…Functional connectivity and volumetric data improve prediction of DBS outcomes
Objective: To determine the clinical utility of neuroimaging markers to predict motor outcomes for deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson…Altered interhemispheric synchrony in Parkinson’s disease patients with levodopa-induced dyskinesias
Objective: Our investigation aimed to explore interhemispheric functional alterations and its corresponding morphological synchronization changes. Background: Levodopa-induced dyskinesias are common motor complication of Parkinson’s disease…Dysfunction in superior frontal gyrus associated with diphasic dyskinesia in Parkinson’s disease
Objective: We aimed to explore alterations in regional brain function associated with diphasic dyskinesia in Parkinson’s disease (PD). Background: Levodopa-induced dyskinesia (LID), which is a common…Motor cerebellar connectivity and future development of freezing of gait in de novo Parkinson’s disease
Objective: To investigate the role of motor cerebellar connectivity in future development of freezing of gait (FoG) Background: Freezing of gait (FoG) in Parkinson’s disease…
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