Cerebro-cerebellar motor networks in clinical subtypes of Parkinson’s disease
Objective: This study investigated functional alterations within the cerebro-cerebellar system in tremor-dominant (TD) and postural-instability-and-gait-disorder (PIGD) subtypes of Parkinson’s disease (PD) using stepwise functional connectivity…Qualification of Digital Endpoints of Function in Healthy Volunteers for Use in a Decentralized Natural History Study in Genetic Parkinson’s Disease (PD)
Objective: Our goal was to qualify digital and wearable devices to assess the Timed Up and Go (TUG) test and gait related parameters in healthy…MRI biomarkers of freezing of gait development in in Parkinson’s disease
Objective: This study investigated longitudinal clinical, structural and functional brain alterations in Parkinson’s disease patients with freezing of gait (PD-FoG) and in those developing (PD-FoG-converters)…White Matter Correlates of Physical Therapy Measures in Parkinson’s disease Patients with Freezing of Gait
Objective: To identify white-matter (WM) correlates of physical therapy (PT)-measures in Parkinson’s disease (PD) patients with freezing of gait (FOG). Background: Significant gap remains in…Effects of gait symmetry manipulation on cortico-subthalamic interhemispheric coupling in parkinsonian patients by use of virtual reality
Objective: The aim of this study is 1) to characterize gait-related neuronal oscillations and functional connectivity changes between cortico-subthalamic network nodes in Parkinson´s disease (PD)…Neural activity during turning in Parkinson’s: influence of dual-task and freezing
Objective: To examine the neural activity during turning in Parkinson’s disease (PD). Background: Turning is impaired in PD with links to freezing of gait (FOG)…Longitudinal structural and functional brain alterations in Parkinson’s disease patients with freezing of gait
Objective: To investigate the cortical/subcortical grey matter (GM) changes and network functional alterations in PD-FoG patients, in PD developing FoG (PD-FoG-converters) and PD not developing…Brain activity of the emotional circuit in Parkinson’s disease patients with freezing of gait
Objective: The aim of this observational study was to assess brain functional MRI (fMRI) activity during a “FoG observation task” in PD-FoG patients relative to…Factors contributing to prefrontal cortical activity during walking and its response to dual-tasking in Parkinson’s disease
Objective: We examined the contribution of clinical, cognitive, and gait characteristics to prefrontal cortex (PFC) activity during walking and its response to dual-task in people…Decreased mesencephalic locomotor region activation explains loss of presynaptic inhibition during step initiation in people with Parkinson´s disease with freezing of gait
Objective: To investigate if decreased mesencephalic locomotor activation (MRL) activation during step initiation in an-event related fMRI protocol would explain the loss of presynaptic inhibition…
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