Protocol for Rapidly Adaptive Deep Brain Stimulation to improve Freezing of Gait in Patients with Parkinson’s Disease
Objective: We aim to evaluate the effectiveness of single threshold adaptive deep brain stimulation (aDBS) for freezing of gait (FOG) in Parkinson’s disease (PD). We…Automated Identification of Freezing of Gait in Parkinson’s Disease Using Q-Learning Analysis during Virtual Reality–Based Gait Task
Objective: To investigate whether a virtual reality (VR)-based gait task can induce freezing of gait (FOG) in Parkinson’s disease (PD) and whether gait trajectory data…Unravelling the neural correlates of visual cueing in Parkinson’s disease
Objective: Visual cueing can compensate for impaired automatic gait control in Parkinson's disease (PD) patients experiencing Freezing of Gait (FOG) by engaging goal-directed motor behaviour1.…Sensory–Motor Discrepancy of Arm Swing During Gait in Parkinson’s Disease
Objective: To examine the discrepancy between perceived and actual arm swing amplitude during gait in individuals with Parkinson’s disease (PD) and to explore the potential…Dynamic Neural States underlying Freezing of Gait in Parkinson’s Disease
Objective: This study aimed to characterize dynamic brain states during freezing of gait in Parkinson’s disease using Hidden Markov Modelling of EEG data. Background: Freezing…MLR–cerebellar network in body-first vs. brain-first PD: functional connectivity and clinical correlation with gait impairment
Objective: This study aims to clarify subtype-specific changes in mesencephalic locomotor region (MLR)-cerebellar functional connectivity(FC)[1][2] between body-first and brain-first Parkinson’s disease (PD) patients[3][4], and to further characterize…Characteristics of Cortical Beta Bursts in Parkinson’s disease
Objective: 1. Do patients with PD experience changes in cortical beta bursts in both the low and high β frequency bands?2. Are bursts of different…Multisite high-definition gamma-tACS combined with rhythmic auditory cued gait enhances network efficiency in patients with Parkinson’s disease
Objective: The study aimed to determine whether high-definition gamma-tACS (hd-γtACS) delivered over the posterior parietal cortex (PPC)-primary motor cortex (M1) and cerebellum (CB)-M1 pathways during…Boosting cerebellum/M1 and PPC/M1 communication via tACS to improve cued gait in Parkinson’s disease patients unresponsive to auditory cueing strategies.
Objective: This study aims to test the contribution of Posterior Parietal Cortex – primary motor cortex and cerebellum - M1 pathways in decreasing gait variability…Cortical Oscillatory Dynamics during Turning in Parkinson’s Disease using OPM-MEG
Objective: To non-invasively characterise cortical oscillatory activity in Parkinson’s disease (PD), with high spatial resolution, during a turning task, and to compare sensorimotor dynamics between…
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