Investigating Hippocampal Subfield and Amygdala Volumes in Parkinson’s Disease with Anxiety
Objective: To determine whether structural changes in the hippocampus and amygdala are associated with anxiety in Parkinson’s disease (PD), and to identify whether these alterations…Neuroprotective Effects of Curcumin on Hippocampal-PPN Circuitry in a Rotenone-Induced Rat Model of Parkinson’s Disease
Objective: This study investigated the neuroprotective effects of curcumin on the hippocampal-pedunculopontine nucleus (PPN) axis in a rotenone-induced rat model of PD. Background: Parkinson’s disease…Age Related Susceptibility of Hippocampal Synaptic Ultrastructure and Spatial Cognition to Chronic Toluene Exposure: A Comparative Study of Immediate and Long Term Effects
Objective: This study delineates the age-dependent susceptibility of hippocampal CA1 circuits to chronic toluene toxicity, specifically investigating whether synaptic degradation is reversible or marks the…The Influence of Glymphatic System Impairment on Cognitive Decline in Parkinson’s Disease
Objective: The study investigated alterations of glymphatic system in both patients and mouse model of Parkinson’s disease (PD) with cognitive impairment (CI), and elucidated the…Human Snca Knock-In Mouse as a Model for Synucleinopathy Research
Objective: Inter-species differences between mouse and human α-synuclein (asyn) may influence aggregation and pathology in animal models, highlighting the need for models expressing human asyn.…Data-driven Longitudinal Trajectories of Hippocampal Volume in Parkinson’s Disease and Across the Neurodegenerative Disease Spectrum
Objective: To elucidate hippocampal (HP) volume trajectories in Parkinson disease (PD) and across the neurodegenerative disease (NDD) spectrum. Background: HP volume is a critical neuroimaging…LED Light as an Inductor of Optogenetic Activation of Astrocytes in Multiple System Atrophy
Objective: The pathogenesis of Multiple System Atrophy (MSA) involves the spread of misfolded α-synuclein from nerve cells to glia and dysfunction of mitochondria and proteasomes,…Predictor of post-deep brain stimulation cognitive decline in Parkinson’s disease patients
Objective: Deep brain stimulation (DBS) is a highly effective treatment for Parkinson’s disease (PD) motor symptoms; however, its benefits can be overshadowed by side effects…Lewy Pathology correlates with neuroinflammation in the hippocampus of Synucleinopathy patients in a subregion specific manner
Objective: The objective of this study is to examine the sub-regional differences in neuroinflammation (NI) in response to Lewy pathology (LP) within the hippocampus of…Hippocampal-striatal interaction and cognitive decline in Parkinson’s disease with mild cognitive impairment
Objective: We aimed to investigate the interaction between hippocampus and dopaminergic pathways in PD with mild cognitive impairment (PD-MCI). Background: Dysfunction of striatal dopaminergic neurotransmitter…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.