Levodopa-Induced Dyskinesia Predicts Falls, Fall-Related Injuries, and Their Consequences in Parkinson’s Disease: A Prospective PPMI Cohort Study
Objective: This study aimed to (i) assess the prevalence and incidence of falls, (ii) identify contributors to falls, and (iii) examine injuries and consequences caused…Probiotic Y7 Intervention Is Associated with Improved Motor, Gut-Related, and L-DOPA-Related Outcomes in a Rat Model of Parkinson’s Disease
Objective: To evaluate whether probiotic Y7 intervention improves disease-related outcomes and influences L-DOPA-related responses in a 6-hydroxydopamine (6-OHDA) rat model of Parkinson’s disease (PD). Background:…Nutritional Status as a Modifiable Determinant of Clinical Outcomes in Parkinson’s Disease: A 12-Month Longitudinal Study in Patients Treated with DBS and L-Dopa
Objective: To analyze longitudinal changes in nutritional status in Parkinson’s disease (PD) patients treated with deep brain stimulation (DBS), compared with pharmacological therapy (L-dopa) and to…Corticobasal Degeneration With Alien Limb Phenomenon and Severe Cognitive Decline: A Levodopa-Resistant Clinical Case
Objective: To describe a clinical case of corticobasal degeneration presenting with alien limb phenomenon, severe cognitive decline, and resistance to high-dose levodopa therapy. Background: Corticobasal…Continuous Subcutaneous Foslevodopa/Foscarbidopa Infusion in Advanced Parkinson’s Disease: Results from a Prospective Real-world Study
Objective: To evaluate the effectiveness and tolerability of continuous subcutaneous foslevodopa/foscarbidopa (LDp/CDp) infusion in patients with advanced Parkinson’s disease (PD) in a real-world setting. Background: In…Clinical Profile of Early-Onset Parkinson’s Disease in a Tertiary Hospital in Oman
Objective: To investigate the prevalence of early-onset Parkinson’s disease (EOPD) among patients attending the movement disorder clinic at a tertiary hospital in Oman. We also…Real-World Experience with Continuous Subcutaneous Foslevodopa/Foscarbidopa (FLC/FCD) in Advanced Parkinson’s Disease: A Single-Centre Cohort Study
Objective: To evaluate efficacy, safety, and discontinuation rates of FLC/FCD in a retrospective cohort of advanced PD patients. Background: Continuous subcutaneous FLC/FCD is a novel…Differential effects of levodopa and subthalamic nucleus deep brain stimulation on the bradykinesia components in Parkinson’s Disease
Objective: To quantify and compare the differential effects of DBS and L-dopa on the individual kinematic components of bradykinesia. Background: Parkinson’s disease (PD) bradykinesia is…Complete Resolution of Troublesome Dyskinesia in People With Advanced Parkinson’s Disease Treated With Foslevodopa/Foscarbidopa: Post Hoc Analysis From a 52-Week Phase 3 Trial
Objective: To evaluate the achievement of complete elimination of troublesome dyskinesia (TSD) and associated changes in Off time, motor aspects of experiences of daily living…Digital Handwriting Analysis: A Useful Tool to Quantify Acute Dopaminergic Response in Parkinson’s Disease
Objective: To evaluate digital handwriting kinematics as a useful tool to quantify the acute motor response to dopaminergic treatment in patients with Parkinson’s disease (PD).…
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