MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Levodopa(L-dopa)"

  • 2025 International Congress

    Atypical Psychosis in Parkinson Disease: A Retrospective Study on 24-Hour Continuous Subcutaneous Infusion Foslevodopa/Foscarbidopa Therapy

    K. Ikenaka, K. Kakuda, Y. Kimura, H. Mochizuki (Suita, Japan)

    Objective: This study aims to identify clinical predictors of continuous subcutaneous infusion (CSCI)-induced psychosis to understand its potential mechanisms and evaluate predictive measures for its…
  • 2025 International Congress

    Pharmacokinetic Analysis of Subcutaneous Levodopa/Carbidopa Delivery With ND0612

    L. Adar, N. Vostokova, I. Hadari Naor, G. Smania, M. Ibrahim, J. Pereira, I. Perlstein, M. Karlsson (Rehovot, Israel)

    Objective: To (i) use a population pharmacokinetic (PK) model to compare predicted levodopa PK parameters when levodopa is delivered as investigational ND0612, as oral immediate-release…
  • 2025 International Congress

    A case of Parkinson’s Disease whose Daily Levodopa/Carbidopa Intestinal Gel dose has been determined by her spouse and prevented Long-term Fluctuations

    Y. Okuma (Izunokuni, Japan)

    Objective: To present a case of Parkinson’s disease (PD) whose daily levodopa/carbidopa intestinal gel (LCIG) dose has been determined by her spouse and prevented long-term…
  • 2025 International Congress

    Utilizing the Levodopa Challenge Test to Clarify Clinical Complaints Following Levodopa Administration: A Case Series

    M. da Silva, C. Ternes, B. de Lima, R. Mesquita, L. Moriyama (Campinas, Brazil)

    Objective: To characterize subjective clinical complaints reported by patients with Parkinson's Disease (PD) following levodopa administration and evaluate the utility of the levodopa challenge test…
  • 2025 International Congress

    Risk of Motor Complications in Early Parkinson’s Disease Patients Treated with Opicapone in the EPSILON study: Effect of Levodopa Dose

    J. Ferreira, O. Rascol, F. Stocchi, A. Antonini, H. Brigas, J. Moreira, JF. Rocha, M. Fonseca, D. Ramos, J. Holenz, W. Poewe (Lisbon, Portugal)

    Objective: This post-hoc analysis of the EPSILON study evaluated whether levodopa dose (<400mg/day vs. ≥400mg/day) and opicapone (OPC) timing (at double-blind [DB] or open-label extension…
  • 2025 International Congress

    Timing And Type Of Adverse Events Following Long-Term Treatment With Levodopa–Entacapone–Carbidopa Intestinal Gel (LECIG) Infusion – Data From The ELEGANCE Interim Analysis

    N. Smith, B. Amlani (Reading, United Kingdom)

    Objective: To evaluate the type and timing of occurrence of treatment-emergent adverse events (AEs) in people with advanced Parkinson’s disease (PD) following up to one…
  • 2025 International Congress

    The efficacy and safety of continuous subcutaneous infusion therapy with foslevodopa/foscarbidopa

    M. Shiraishi, N. Takao, Y. Nakano, Y. Yamano (Kawasaki City, Japan)

    Objective: To clarify the actual status of CSCI therapy, cases in which CSCI therapy was started at our hospital were investigated. Background: Continuous subcutaneous infusion…
  • 2025 International Congress

    Effect of Opicapone on Sleep-Related Complaints and Non-Motor Burden in Parkinson’s Patients: A Post-Hoc Analysis of the OASIS Trial

    J. Ferreira, M. Gago, R. Costa, M. Fonseca, H. Brigas, D. Martins, J. Holenz, C. Trenkwalder (Lisbon, Portugal)

    Objective: To assess the effect of opicapone (OPC) on different sleep complaints and non-motor symptoms (NMS) in fluctuating Parkinson’s disease (PD) patients with sleep disturbances.…
  • 2025 International Congress

    Patient And Clinician Perceptions Of Disease Improvement With Levodopa–Entacapone–Carbidopa Intestinal Gel (LECIG) In Advanced Parkinson’s – Data From The ELEGANCE Interim Analysis

    N. Smith, B. Amlani (Reading, United Kingdom)

    Objective: To evaluate clinicians’ and patients’ views of the level of improvement in Parkinson’s disease (PD) achieved following up to two years of treatment with…
  • 2025 International Congress

    Levodopa response in pathology-confirmed Parkinson’s Disease, Multiple System Atrophy and Progressive Supranuclear Palsy

    V. Arca, J. Jurkeviciene, S. Wrigley, P. Cullinane, J. Parmera, Z. Jaunmuktane, T. Warner, E. de Pablo-Fernandez (London, United Kingdom)

    Objective: to describe the rate of levodopa response, phenotypical characteristics, prognostic implications and pathological features in a large cohort of patients with pathology-confirmed Parkinson’s disease…
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