L-Dopa responsiveness in early Parkinson’s disease: Results from the United Kingdom Tracking Parkinson’s study
Objective: We wanted to evaluate L-dopa responsiveness in a large cohort of patients with recently diagnosed Parkinson’s disease (PD) using an acute L-dopa challenge test.…High dose of levodopa and Segawa disease
Objective: To analyze the dose-dependent effects of levodopa on the symptoms of the disease in our case. Background: In 1976, Segawa et al. reported dopa-responsive…Effects of L-DOPA on Quantitative Gait Parameters Measured with Wearable Sensors
Objective: To quantify and validate the ability of wearable sensors to detect response to symptomatic medication in Parkinson's Disease (PD). Background: While clinical visual assessment…Intrastriatal Fyn silencing as a gene therapy strategy to manage levodopa induced dyskinesia in a mice model of Parkinson’s disease
Objective: To genetically abrogate Fyn expression to reduce levodopa induced dyskinesia (LID) in the 6-OHDA mice model of Parkinson’s disease (PD), using intrastriatal-injected lentiviral (LV)…Design of a Pharmacokinetics Study with Multiple Doses of Accordion Pill™ Carbidopa/Levodopa in Patients with Parkinson’s disease
Objective: To perform a pharmacokinetic (PK) study of the Accordion Pill™ carbidopa/levodopa (AP-CD/LD) and to determine if multiple doses can provide continuous delivery of LD.…A phase Ib trial studying the safety and tolerability of IRL790 in patients with Parkinson’s disease and levodopa-induced dyskinesia
Objective: The primary objective was to investigate the safety and tolerability of IRL790 in PD patients with LID in a randomized controlled trial. Background: IRL790…Comparative results between preoperative acute levodopa challenge test and deep brain stimulation
Objective: Our aim is to compare motor clinical benefits after acute levodopa challenge test, with those obtained further with deep brain stimulation (DBS). Background: DBS…Identification of L-DOPA “on/off” states using speech-based analysis in Parkinson’s disease subjects
Objective: The aim of this study is to assess the use of semantic, prosodic, and acoustic speech features to better characterize PD signs with respect…Future doctors as health educators: Undergraduate medical students raise awareness and unite for Parkinson’s disease
Objective: To highlight the role of undergraduate students in raising the awareness about Parkinson's disease among peers and public. Encouraging the students to take responsibility…The Interface of advanced therapies as Parkinson’s disease progresses – case reports
Objective: To explore the practical benefits and challenges of adding duodenal levodopa-carbidopa intestinal gel infusion (LCIG) to subthalamic nucleus deep brain stimulation (STN DBS) in…
- « Previous Page
- 1
- …
- 50
- 51
- 52
- 53
- 54
- …
- 70
- Next Page »