Optimization of a neuromelanin MRI protocol for use in a longitudinal study of substantia nigra depigmentation in early Parkinson’s Disease (the InsIght-PD study)
Objective: To optimize a neuromelanin-MRI (NM-MRI) protocol for robust and timely change analysis; and acquire serial NM-MRI data in controls and early Parkinson’s Disease (PD),…Neuroimaging associations to gait impairments in progressive supranuclear palsy
Objective: The aim of this study was to determine how multimodal imaging biomarkers were related to abnormalities in three-dimensional motion-based gait and balance measurements in…Intrasubject subcortical quantitative referencing to make quantitative MRI sensitive to Parkinson’s disease
Objective: To assess the changes in R2* occurring in PD patients compared to controls, a multicenter transversal study was carried out in a large cohort of…Neurofilament light is related to fractional anisotropy in early Parkinson’s diesease
Objective: We aimed to determine whether plasma NfL reflects changes in brain white matter integrity as measured using fractional anisotropy (FA) in patients with early…A retrospective review of clinical and MRI/CT radiological correlation in progressive supranuclear palsy (PSP)
Objective: To investigate the clinical and MRI/CT radiological correlation to improve the diagnosis and management of PSP Background: PSP is a rare progressive neurodegenerative disease…The evaluation of the swallow tail sign in patients with parkinsonism or gait disorders
Objective: The goal of the study is to evaluate the reliability of swallow tail sign which claimed to be specific for Parkinson's disease. Background: Swallow…Longitudinal Study of Grey Matter Nuclei in Early Parkinson’s Disease using Diffusion Kurtosis Imaging
Objective: We aimed to determine whether microstructural characteristics of key grey matter nuclei would be differentially altered between baseline and two-year timepoints in Parkinson’s disease…Quantitative susceptibility mapping and blood neurofilament light chain differentiate between parkinsonian disorders
Objective: We employed Quantitative susceptibility mapping (QSM) to assess iron deposition in a larger sample size and explore whether combining QSM and NfL can improve…Parkinson Disease with, but not without, Cognitive Decline Reveals Advanced Brain Aging
Objective: To investigate “brain age” in Parkinson disease (PD) with and without cognitive decline, and its correlation with motor and cognitive performance. Background: Although brain…Normal-sized Perivascular Space in Basal Ganglia Related to Motor Phenotypes in Parkinson Freezers
Objective: With 7T MRI, we aimed to study the relationship between the initial motor phenotype of Parkinson’s disease (PD) and normal-sized PVSs (nPVSs) burden in…
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