MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Magnetic resonance imaging(MRI)"

  • 2024 International Congress

    Diffusion MRI and Machine Learning Distinguish Alzheimer’s Disease and Dementia with Lewy Bodies

    R. Chen, W. Wang, A. Barmpoutis, D. Vaillancourt (Gainesville, USA)

    Objective: This study reports recent updates in the development of a support vector machine learning model to discriminate between dementia variants (i.e., Alzheimer’s disease (AD)…
  • 2024 International Congress

    Increased Brain Free Water is Associated with Regional Gene Expression in Parkinson’s Disease

    D. Zhang, J. Yao, H. He, T. Wu (Beijing, China)

    Objective: In this study, we used brain free water scores and regional gene expression profiles from the Allen Human Brain Atlas transcriptomic data to investigate…
  • 2024 International Congress

    The 2-Minute Walking Test Predicts Aerobic Fitness, Motor Function, and Brain Health in Parkinson’s Disease

    E. Uc, V. Magnotta, E. Axelson, J. Dawson, M. Mani, A. Comellas, J. Kline, N. Narayanan, D. Mcgehee, S. Anderson, C. Weber, W. Darling (Iowa City, USA)

    Objective: To determine the association of performance on the 2-Minute Walking Test (2MWT) with aerobic fitness, motor and cognitive function, and brain health in mild…
  • 2024 International Congress

    White Matter Tractography in Spinocerebellar Ataxia type 1 and 2 in comparison with Healthy Controls

    P. Pankaj, A. Srivastava, M. Kumar, S. Kumaran, A. Garg, R. Agarwal, A. Nehra (New Delhi, India)

    Objective: To assess and quantify microstructural white matter atrophy in brain of spinocerebellar ataxia (SCA) types SCA1 and SCA2 patients in comparison with healthy subjects.…
  • 2024 International Congress

    A Phase 2 Study of ATH434 a Novel Inhibitor of α-Synuclein Aggregation for the Treatment of Multiple System Atrophy

    D. Stamler, C. Wong, P. Trujillo, M. Bradbury, C. Lucas, D. Claassen (Newark, USA)

    Objective: Describe baseline fluid and neuroimaging biomarker data of an early MSA study population Background: MSA is a rapidly progressive neurodegenerative disorder characterized by aggregated…
  • 2024 International Congress

    Developing a Supervised Machine Learning Model for Long-Term Cognitive Status Prediction in Parkinson Disease

    L. Saadatpour, A. Vijayakumari, D. Floden, H. Fernandez, B. Walter (Cleveland, USA)

    Objective: The study aims to develop a supervised machine learning (ML) model to predict long-term cognitive outcome in patients with Parkinson disease (PD). Background: Cognitive…
  • 2024 International Congress

    Identification of Brain Atrophy Subtypes in Prodromal and Overt Synucleinopathies: A Multicenter Study

    S. Joza, A. Delva, C. Tremblay, A. Vo, J-F. Gagnon, R. Postuma, P. Dusek, M. Hu, J. Klein, J-P. Taylor, J. O'Brien, M. Firbank, A. Thomas, P. Donaghy, S. Lehericy, I. Arnulf, M. Vidailhet, J-C. Corvol, M. Sommerauer, S. Röttgen, S. Lewis, E. Matar, K. Ehgoetz Martens, L. Churchill, R. Camicioli, H. Chertkow, P. Borghammer, K. Knudsen, A. Hansen, D. Arnaldi, B. Orso, P. Matiioli, A. Dagher, S. Rahayel (Montreal, Canada)

    Objective: To identify unique subtypes of synucleinopathy with distinct spatiotemporal patterns and trajectories of brain atrophy and disease burden. Background: The synucleinopathies manifest as a…
  • 2024 International Congress

    Longitudinal Structural and Functional Correlates of Progression in Isolated Rapid Eye Movement Sleep Behaviour Disorder

    L. Churchill, YC. Chen, J. Anderson, A. Ignatavicius, SJG. Lewis, E. Elie (Camperdown, Australia)

    Objective: To identify progressive structural and functional imaging alterations in a longitudinal cohort of patients with isolated rapid eye movement sleep behavior disorder (iRBD). Background:…
  • 2024 International Congress

    Fixel Analysis of Diffusion Imaging in Cerebellar Tracts as a Quantitative Marker of Disease Progression in Spinocerebellar Ataxia

    D. Arpin, S. Subramony, D. Vaillancourt, M. Burns (Gainesville, USA)

    Objective: This study aimed to identify white matter changes in the brain of presymptomatic and early-stage SCA1 and SCA3 mutation carriers using fixel-based analysis of…
  • 2024 International Congress

    Prospective Study of Gait and Multimodal MRI Biomarkers for Multiple System Atrophy

    F. Marchand, R. Viard, D. Devos, L. Defebvre, T. Ollivier, D. Guehl, G. Kuchcinski, C. Moreau (LILLE, France)

    Objective: We aimed to develop new multimodal biomarkers allowing objective monitoring of early MSA progression to improve outcome definition for future neuroprotective trials. Background: MSA…
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